Cells that lacked tryptase showed major changes, including a loss of their cellular identity and they also started to proliferate in an uncontrolled way. (sciencedaily.com)
These targets include, for example, serine proteinases tryptase, chymase, cathepsin G, which are enzymes that break down proteins, as well as 5 - lipoxygenase - activating protein FLAP, 15 - lipoxygenase - 1, prostaglandin - D2, and proinflammatory cytokines such as TNF - alpha, IL - 4, IL - 6 and IL - 17. (sciencedaily.com)
«Cells that lack tryptase start to proliferate in an uncontrolled fashion and lose their identity. (sciencedaily.com)