We have used the information gained from these studies to identify key pathways and mechanisms involved in tumor resistance to chemotherapy and radiation, including the role of colorectal cancer stem cells. (lerner.ccf.org)
Researchers report that PD - 1 / PD - L1 monoclonal blocking antibody allows T cells to remain active and fight malignant evolution, subsequently preventing tumor resistance. (cancernetwork.com)
She showed that tissue macrophages have unique functional attributes that may have critical clinical implications, including a unique ability to resist genotoxic stress, which contributes to graft - versus - host disease and impacts tumor resistance to radiotherapy. (sciencemag.org)