The premise of the book was that if you didn't find your own unique significance (voice), neither you nor your organization would be able to achieve greatness. (edutopia.org)
Further, they should be able to understand the loving and unique significance of conjugal intercourse, which lies not mainly in the pleasure it may give the spouses, but in the unparalleled way by which it expresses the total and exclusive self - gift they made to one another in marrying. (faith.org.uk)
The Gospels attribute unique significance to the cross. (religion-online.org)