I suspect relevance to usual intakes in humans played a role, too. (nutritionfacts.org)
However, very high intakes of sucrose or fructose (2 - 3 times usual intake), or high carbohydrate diets (70 - 80 % carbohydrate) can result in elevated plasma triglycerides which can increase heart disease risk. (fitnessandpower.com)
Using biomarker data to adjust estimates of the distribution of usual intakes for misreporting: application to energy intake in the US population. (completehumanperformance.com)