But researchers analyzing various tissue types this year, looking for mutations linked to the disease, have found that not all genetic alterations should be targeted equally. (sciencenews.org)
Researchers have long known that chemical modifications, a collection of «marks» on DNA known as the epigenome, play a key role in how cells operate by guiding differences between various tissue types in a given individual's body, despite the fact that they all carry the same genetic code. (jhsph.edu)
But since they are made from embryonic stem cells, which can go on to become any of the body's various tissue types as well as form a type of tumor, the FDA was concerned that some pure stem cells would remain in the transplanted RPE population. (robertlanza.com)