If vascular growth factors called angiopoietins attach to the Tie2 receptor, the growth of new capillaries initially stops and existing ones can mature. (sciencedaily.com)
The inflammation associated with rosacea promotes additional vascular growth (see Role of Excess Blood Vessels), and this process builds on itself, with more blood vessel growth allowing for more inflammation, which only creates more blood vessel growth, etc.. (rosacea-research.org)
The team, led by Sérgio Dias, had previously shown that leukemic cells activate certain molecular signals, namely a cell signalling pathway controlled by the Endothelial Vascular Growth Factor (VEGF), which allow cancer cells to survive despite chemotherapy. (sciencedaily.com)