I only ran into a few weird spots where I found it incredibly difficult to stay hidden, or otherwise keeping enemies unaware of my presence. (giantbomb.com)
However, if it is something like weird spots indicating a rash, take it to the vet. (wikihow.com)
I see their quiet and subtle evangelizing harmless (you have to look in weird spots on their wrappers to find the bible verses). (religion.blogs.cnn.com)