The technology now available for sequencing whole viruses within days means new human respiratory viruses are being discovered at the rate of about one per year, says John Oxford of Queen Mary College in London. (newscientist.com)
But because the replicon does not produce whole viruses and their attendant envelope proteins, researchers can not use it to determine how HCV infects cells — a critical question that has frustrated all comers. (sciencemag.org)
(A and B) Pandemic H1N1 reactive mAbs isolated from infected patients (1000, EM, 70, 1009) were assayed for binding to annual H1N1 influenza strain whole virus. (jem.rupress.org)