Many times one takes action only when these produced irreversible effects on people's health. (dotearth.blogs.nytimes.com)
This implies that the urban environment imposes a challenge to developing birds, with potentially irreversible effects on lifespan. (rsbl.royalsocietypublishing.org)
During pregnancy and early infancy, iodine deficiency can cause irreversible effects. (ods.od.nih.gov)