Confocal microscopy is a type of microscope that uses lasers to capture high-resolution and three-dimensional images of samples. It focuses on a small area at a time, and by using special detectors, it filters out unwanted light to create a clear and detailed image. This method allows scientists to closely examine the structure and details of cells or objects at a specific point in the sample.
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Kozlowski tackled that problem computationally; using the popular MATLAB programming environment, she and her colleagues developed an algorithm that classifies the shapes of microglia in
confocal microscopy images with 90 % accuracy.
So the Bessel beam can scan a cell with the same total flux as the light spots used
in confocal microscopy, but that flux is distributed among the seven beams and the cell isn't flooded with excess light; thus, the cell isn't damaged nearly as quickly.
These models were tested with real measures of cell length in Arabidopsis roots, carried out
with confocal microscopy in CRAG.
«Furthermore, adapting in vivo corneal
confocal microscopy for use in tracking HIV - induced PNS damage in patients may be of great value to identify early PNS damage independent of performing skin biopsies.»
In addition, I am actively involved in numerous investigations utilizing in vivo
corneal confocal microscopy for the diagnosis and characterization of ocular surface diseases in a variety of animal species.
A technique
called confocal microscopy captures images like the one above, the first - place winner of this year's Nikon Small World photography contest.
To date, available microendoscopic devices use the principle of
fluorescence confocal microscopy, and thereby mainly analyse the spatial distribution of specific endogenous or exogenous fluorophores.
The research team is now exploring additional biological applications for the new system and is working to extend the method to other microscope modalities, such
as confocal microscopy.
Using high -
resolution confocal microscopy, the scientists discovered that the microorganism thwarts the immune system by emitting a toxin and immobilizing hemocytes, cells that would normally kill it.
To address this need, here we use Drosophila embryos, specifically embryonic hemocytes, as models for studying the early stages of infection in real - time using time
lapse confocal microscopy.
He studies DNA and RNA quadruplexes, nucleic acid structures that were first visualized
via confocal microscopy in fixed, dead cells.
Another popular technique for 3D cell imaging called spinning
disc confocal microscopy can't image samples nearly as long as Betzig's technique, but it is still better for imaging thick cells and tissue.
Image captured by
confocal microscopy at the Molecular Imaging Platform of the Research Institute of the McGill University Health Centre.
We then
combined confocal microscopy and electrophysiology to explore the interactions between temperature, adrenergic stimulation and contraction frequency on the temporal and spatial properties of Δ [Ca2 +] i, and the excitation profiles of AP and ICa in isolated myocytes.
High - speed Ca2 + imaging, using swept -
field confocal microscopy, showed the Ca2 + influx through the reverse - polarity channels was not localized to the hair bundle, but distributed across the apical plasma membrane.
To come to a structural understanding of nuclear organisation, we will explore and further improve correlative imaging approaches, combining live
cell confocal microscopy, super-resolution and electron tomography to unravel the structure and mechanisms of NPC assembly and disassembly.
On confocal microscopy, the diabetic patients also had a significantly lower corneal nerve fiber density, indicating loss of corneal nerve fibers.
7 - day - old Enchytraeus coronatus (annelid worm) embryo (250x)
Confocal microscopy Annette Bergter Department of Zoology University of Osnabruck Osnabruck, Germany
Spirorbis sp. (aquatic worm)(100x)
Confocal microscopy Jens Rüchel Department of Zoology University of Osnabruck Osnabruck, Germany
Improvements of similar magnitude in imaging speed and a twofold gain in axial resolution relative to
confocal microscopy yield 4D spatiotemporal resolution high enough to follow fast, nanoscale dynamic processes that would otherwise be obscured by poor resolution along one or more axes of spacetime.
Transmitted
light confocal microscopy image (left) of microcapsules consisting of a PLG shell and aqueous, fluorescent BSA core created using Orbis's technology.
TriM Scope II is a modular multi - photon /
confocal microscopy platform combining single - and multi-beam operation for deep, in - vivo imaging.
Confocal microscopy further demonstrated an extensive network of nestin - positive cellular processes emanating from the transplanted cells present within the neurosensory retina (Figure 6C), which was not observed in the subretinal hNPCctx population.
Functional imaging using in vivo
confocal microscopy which allows the analysis of vaso - activity phenomena during hypoxia, of ischaemia reperfusion events, or of homing cells in pathologic processes, such as tumours or inflammatory diseases.
I have learned techniques from flow cytometry to the state - of - the -
art confocal microscopy, as well as many other essential cellular and molecular immunology techniques.
Confocal microscopy through cells labelled with the apical marker ATP1B1 demonstrated that POS are internalized by iPS - RPE (Fig. 4A and Movie S1).
The adherent blood cells over their luminal surface were visualized by scanning electron microscopy (SEM) and by
confocal microscopy after immunostaining with mouse anti-CD41 antibody tagged with PE, rabbit anti-fibronectin and mouse anti-β − actin.
Similar to the experiment in Fig. 3B, blood vessel volumes in control and GDF11 - treated mice were measured by using z - stack images obtained
from confocal microscopy.
Demonstrated expertise in
handling confocal microscopy and Nuclear Magnetic Resonance, along with exceptional insight into chemical regulations, make me an excellent person to hire.