Sentences with phrase «actin filaments»
"Actin filaments" are thin structures present in our cells that help them with movement and maintaining their shape. They act like flexible scaffolding inside our cells and play a crucial role in various biological processes. Full definition
Aside from the variation of paracrine factors between male and female cells, the team also found important differences in organization, distribution and morphology of actin filaments in male and female hAMSCs.
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She revealed that GMF, a protein that promotes the disassembly of branched actin filament networks, controls the size and lifetime of protrusions in border cell clusters migrating in fruit fly egg chambers.
Side - binding proteins modulate actin filament dynamics.
On the basis of analysis of this system, we proposed a model for filopodial formation in which actin filaments of a preexisting dendritic network are elongated by inhibition of capping and subsequently cross-linked into bundles by fascin.
«These findings demonstrate that efficient actin filament disassembly by GMF is essential for rapid dynamics of cell protrusions, and that this dynamics are important for cell migration in a three - dimensional tissue environment,» says Minna Poukkula from the research group of professor Pekka Lappalainen.
«First actin filaments, a very important component of the cytoskeleton, serve as a mould for the deposition of the chitin of the matrix.
Omi cleaves actin filaments in the cytoskeleton, and the decrease in actin suppresses the activity of p130Cas, a focal adhesion signaling protein that promotes the formation of lamellipodia.
New research at Rice University suggests actin filaments that control the shape of neuron cells may also be the key to the molecular machinery that forms and stores long - term memories.
Wolynes and his co-authors, Rice graduate student Mingchen Chen and postdoctoral researcher Weihua Zheng, determined the path to encoding memories may lie in the way actin filaments - the «muscle» part of the cytoskeleton in every eukaryotic cell - pull upon and stabilize soluble cytoplasmic polyadenylation element binding proteins (CPEB) into longer, insoluble prion - like fibers.
A team from Kent's School of Biosciences uncovered the mechanism whereby the physical properties of the internal structures within cells — known as actin filaments — are «fine - tuned» to undertake different functions.
Growth of lamellar networks of actin filaments after the addition of the new compounds (compare the cell contours on the left and right).
The switch - associated protein 70 (SWAP - 70) bundles actin filaments and contributes to the regulation of F - actin dynamics.
Actin filaments form different polymer networks with versatile mechanical properties that depend on their spatial organization and the presence of cross-linkers.
We propose that fascin is a key specific actin cross-linker, providing stiffness for filopodial bundles, and that its dynamic behavior allows for efficient coordination between elongation and bundling of filopodial actin filaments.
Fluorescence recovery after photobleaching of GFP - tagged wild - type and S39A fascin showed that dephosphorylated fascin underwent rapid cycles of association to and dissociation from actin filaments in filopodia, with t (1/2) < 10 s.
The control sample shows clear actin filaments (cables), whereas the drug - treated cells show a punctuate distribution of F - actin.
Scientists are interested in the timing of the movement of myosin along actin filaments which is driven by the power stroke — a process called lever arm swing.
In muscles, myosins generate movement by interacting with actin filaments, a fibrous track they can bind to and move along.
Chiolo and colleagues discovered that this relocalization depends on Arp2 / 3 - dependent dynamic actin filaments.
She wrote her dissertation on pollen sterility in petunias, but she also studied cell structure, which led her back to animals and a postdoc at the Scripps Research Institute in San Diego, California, where she studied a protein on the ends of actin filaments.
In this way, they uncovered the mechanism which determines the functional characteristics of actin filaments in all cells and orchestrates cellular activity.
Very large aggregates can be formed from protein subunits, for example many thousand actin molecules assemble into an actin filament.
Not only did the myosin head hang onto the actin filament, but its tail — thought to be stiff for pulling during contraction — stretched a bit.
The scientists propose that Src42A — a protein that belongs to the family of kinases that regulates the structure of the actin filament — is one of the main contributors to this system.
When that protein is added to the receptor, the receptor gets taken out of its nanodomain and becomes caught up in the actin filaments that form the cell's cytoskeleton.
Polymerization is the chemical reaction that allows for the formation of molecular chains, in this case, actin filaments.
Muscle shortening or contraction depends on these filaments sliding against each other, and requires that the actin filaments are anchored in planes, called Z - discs.
While some of these actin filaments appear to completely stable, providing a framework for the cell, others are more dynamic, allowing the cell to respond rapidly to changes in its environment.
The cytoskeleton is mainly composed of actin filaments and microtubules.
We are probing this «molecular motor» by attaching a polystyrene sphere to an actin filament and using the optical tweezers to grab onto the bead.
When the myosin head strokes against the actin filament, the motion is sensed by a photodiode at the viewing end of the microscope.
Derived from supramolecular chemistry [4], the new compounds synthesized by the researchers have original properties: within several minutes, they bring about the growth of lamellar networks of actin filaments.
One of the goals of this work is to measure the force generated by a single myosin molecule pulling against an actin filament.
He doesn't know where he's going, but his built - in bias to walk forward eventually gets the vesicle to its destination at the end of the actin filament.
Normally the actin cortex is able to counter the forces applied to it, and even when some damage to the network is incurred, it is quickly fixed by proteins that can reassemble the actin filaments.
Once the actin filament network is fragmented, the bile will push the cell membrane into the cell, through the disrupted actin network.
Plant cells contain two major cytoskeletons, i.e. microtubules (MTs) and actin filaments (F - actin), which help cells to maintain their shape, provide mechanistic support and enable the cells to divide and move.
A group of plant biologists at the Institute of Transformative Bio-Molecules (ITbM) of Nagoya University, the University of Tokyo, the Gregor Mendel Institute, and the University of Kentucky, has reported in the journal Proceedings of the National Academy of Sciences, on their discovery on how the plant's egg cells initially lose their skeletal pattern upon fertilization and are reorganized by two major cytoskeleton components in the cell, microtubules (MTs) and actin filaments (F - actin).
It is primarily used to process images of amyloid fibrils, though it has also been tested on TMV and actin filaments.
Higher magnifications of ultrathin sections shown in C and G indicate the presence of electron - dense DAB precipitates adjacent to F - actin filaments.