"Acute leukemia" is a medical term used to describe a type of cancer that affects the blood and bone marrow. It means that the cancer grows quickly and spreads rapidly, making it more severe and serious.
Full definition
AML is one of the most deadly types of leukemia and the most common type
of acute leukemia in adults; it increases in frequency as we age.
Study in partnership with the Alliance for Clinical Trials in Oncology is the first large controlled trial to show overall survival benefit in FLT3 - mutated AMLAML is the most
common acute leukemia in...
Combined with chemotherapy, Druker says, «this will lead to better treatments
for acute leukemia.»
Previously, MDS was commonly referred to as a preleukemic condition (and it is still sometimes called pre-leukemia) because some people with MDS
develop acute leukemia as a complication of the disease.
One such mutation, found in about 25 % of
acute leukemia patients, involves a gene known as FLT3, which encodes an enzyme called a kinase that usually promotes cell division in a controlled way.
None of the 4219 people studied were found to have a mutation in NPM1, the most common
acute leukemia gene mutated in up to 40 per cent of cases.
These observations indicate that the gene for a transcription factor is located at the breakpoint of a consistently recurring chromosomal translocation in
many acute leukemias and suggest a direct role for alteration of such factors in the pathogenesis of some malignancies.
We have also identified a group of CD1c - restricted T cells that recognize a leukemia - associated lipid antigen and
kill acute leukemia frequently expressing CD1c.
Long term follow - up of individuals with known or suspected familial MDS / acute leukemia syndromes
AML is the most common
acute leukemia affecting adults and is a disease that starts in the bone marrow, but can quickly spread throughout the blood to other organ systems.
Importantly, when mice received lethal doses of host - type
acute leukemia cells, administration of VPA did not impair GVL activity and resulted in significantly improved leukemia - free survival.
Handler's critically acclaimed first memoir, «Time on Fire: My Comedy of Terrors,» chronicling his astonishing recovery
from acute leukemia over 25 years ago, was published in 1996.
Missing First - choice goalkeeper Carl Ikeme has not played since announcing in July that he had been diagnosed
with acute leukemia.
Thomas Look and colleagues use a type of genomic screen and identify abnormal HGF expression as a crucial factor for development of a class
of acute leukemia in leukemia cell lines and clinical samples.
Her mother, Mechtild, had been diagnosed the previous year with
acute leukemia.
Those of us who love and esteem him pray for a miracle that will cure the rare forms of
acute leukemia that now afflict him.
Ikeme played no part in the team's promotion back to the elite division having been diagnosed with
an acute Leukemia but was full of praises for Nuno Espirito Santos» side.
Research on antimetabolites of nucleic acid purines led to drugs for the treatment of
acute leukemia (6 - mercaptopurine and thioguanine), gout and hyperuricemia (allopurinol), and herpesvirus infections (acyclovir), and for the prevention of organ transplant rejection (azathioprine).
Leukemia researcher Brian Druker of Oregon Health and Science University praises the work, calling FLT3 «one of the best targets in all of
acute leukemia, because it's one of the most common.»
They also include the newly updated World Health Organization classification of myeloid neoplasms and
acute leukemia, also published in the journal Blood.
However, about 15 percent of patients on immunosuppressives develop cancer of the blood —
acute leukemia and myelodysplastic syndromes — months or years following treatment.
Aminopterin is a toxin that in the 1940s was the first drug used that produced «durable remissions in children with
acute leukemia,» says Andre Rosowsky, a professor of adult oncology at the Dana - Farber / Harvard Cancer Center.
Researchers at the University of Michigan Comprehensive Cancer Center have developed a new drug candidate that shows potential in laboratory studies against a rare type of
acute leukemia.
Among these, the genes responsible for inherited forms of
acute leukemia and myelodysplastic syndrome are the best characterized.
For example, the following three genes are known to cause inherited forms of MDS and
acute leukemia:
As many as 30 percent of patients who survive childhood Hodgkin lymphoma develop a secondary cancer after diagnosis, primarily breast cancer, non-Hodgkin lymphoma, thyroid cancer or
acute leukemia.
Acute leukemia is a fast - growing cancer that usually gets worse quickly.
Myeloproliferative neoplasms, or MPNs, are a group of chronic blood cancers with the potential to rapidly progress to a more advanced stage or to
an acute leukemia.
Functional intra-tumor heterogeneity and determinants of relapse / non-response to treatment in acute leukemia
Dr. Volanakis is interested in the genetic and epigenetic events that contribute to the pathogenesis and progression of
acute leukemia.
So for some cancers on blood like
acute leukemia for example, the stage existing doesn't really apply and just — it's just the whole bone marrows involved with acute leukemia.
Acute leukemias can develop in months or weeks; while chronic leukemias develop over a period of months or years.
28Orsi L. et al. (2015) Parental smoking, maternal alcohol, coffee and tea consumption during pregnancy, and childhood
acute leukemia: the ESTELLE study.
Zinc supplementation in children and adolescents with
acute leukemia.
Cancer in general is a devastating disease, but your dog's prognosis is better if he develops the chronic form of canine leukemia instead of
acute leukemia.