Nonetheless, on page 1168 of this issue, Wilson et al. (2) report the facile nucleophilic
alkylation of benzene accomplished through highly reactive alkylcalcium nucleophiles.
Because «like species repel,» electron - rich species should not react with other electron - rich species, so benzene should never undergo direct
nucleophilic alkylation.
The intrinsic chemical promiscuity of Bardoxolone results
in alkylation of a large number of proteins [37].
Demonstration by real - time polymerase chain reaction that cellular
DNA alkylation by novel aminoindoline compounds affects expression of the protooncogene c - myc.
His graduate work involved the investigation of
toluene alkylation on zeolites, and studying the acid - base properties of zeolites.
Stefan L. Ameres, Institute of Molecular Biotechnology «SLAMseq: Thiol -
linked alkylation for the metabolic sequencing of RNA»
The recognition that these silver ions act via mild oxidation and
then alkylation (binding) makes good sense in terms of its broad action and lack of toxicity to mammals with their extensive antioxidant defense systems.
Operated sulfur recovery units and
alkylation unit in a safe, reliable and environmentally responsible manner.
The chemical reactivity of these groups leads to
alkylation of reactive thiols and generation of ROS.
Kobayashi K, Narumi T, Oishi S, Ohno H, Fujii N. Amino acid - based synthesis of trifluoromethylalkene dipeptide isosteres by alcohol - assisted nucleophilic trifluoromethylation and organozinc - copper - mediated S (N) 2»
alkylation.