"Allelic variation" refers to the different versions of a gene that exist within a population or among individuals. Genes come in multiple forms called alleles, and
allelic variation occurs due to small differences or changes in the DNA sequence of these alleles. This variation can lead to differences in traits or characteristics among individuals, such as eye color or susceptibility to certain diseases.
Full definition
CONCLUSIONS: These results suggest that the behavioral expression of
allelic variation in MAOA activity is sensitive to social experiences early in development and that its functional outcome might depend on social context.
We examined the influence of a
common allelic variation in the dopamine receptor D4 (DRD4) gene and caregiver quality on temperament in early childhood.
Consistent with a causal relationship, (16) reports that the prevalence of limited physical functioning in aging varies depending on
p16Ink4a allelic variation, consistent with variations in rate of stem cell attrition with senescence.
Examples include the study of
allelic variation in the human genome and the development of computational methods for the discovery of cancer - associated genes and diagnostic cancer markers using genomic profiles derived from different tumor types.
Socio - economic status covaries with central nervous system serotonergic responsivity as a function of
allelic variation in the serotonin transporter gene - linked polymorphic region
BACKGROUND:
Allelic variation of the monoamine oxidase A (MAOA) gene has been implicated in conduct disorder and antisocial, aggressive behavior in humans when associated with early adverse experiences.