These studies have been questioned as the genetic variant required for narcolepsy protects
against autoimmune type 1 diabetes.
Doxycyline is typically combined with niacinamide, a Vitamin B derivative, to
treat autoimmune type skin disorders.
Finland has the highest rate of
autoimmune type 1 diabetes in the world, followed by Sweden.
Patients with LADA — a form of
autoimmune type 1 diabetes in adulthood — can be distinguished from patients with non-autoimmune type 2 diabetes by means of the antibody reaction affinity to the enzyme glutamic acid decarboxylase (GAD).
Final goal of Immune - mediated diseases Unit is to better understand immune - mediated diseases (i.e.,
autoimmune type 1 diabetes, or T1D, and rejection of tissues / organs after transplantation) and to define new approaches for their prevention and / or treatment.