Sentences with phrase «axonal projections»
"Axonal projections" refers to the long branches or extensions of nerve cells (neurons) that transmit signals or information to other parts of the body. These projections help neurons communicate and relay signals across different regions of the brain and nervous system. Full definition
Sitting at the top of this genetic cascade is the Sim1 gene, which also controls both the segregation and axonal projections of the PVN and SON.
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These cells have dozens, often hundreds, of branching axonal projections — output channels from the cell body of the neuron — that lend the full structure of a chandelier - like appearance.
In conclusion, our findings suggest that microstimulation, with its anatomical precision, physiologic - level currents, and action via axonal projections, holds promise for modification of memory circuits and thus for the treatment of memory impairments in people suffering from neurological disorders.
The latter is particularly important for the establishment of long axonal projections, which requires coordinated long - range organelle transport.
Furthermore, the success of this project can lead to the development of novel axon - regenerating therapeutics that could transform the clinical treatment of angle - closure glaucoma and other types of optic neuropathies, as well as have the potential to be adapted to regenerating the long - distance axonal projections damaged by spinal cord injury, brain trauma, and white matter stroke.
When the function of these proteins is disrupted, chandelier cells have fewer, more disorganized, axonal projections.
In addition, high frequency stimulation delivered via macroelectrodes has been shown to inhibit nearby neuronal somata, while also providing excitation to axonal projections, indicating that small changes in electrode location could lead to substantially different results (Herrington et al., 2016).
An intriguing clue to this selectivity is provided by Setola et al., who identify a truncated form of SMN1 that arises from an alternative spliced SMN1 transcript that is preferentially expressed in the axonal projections of developing motor neurons.