Sentences with phrase «behavioral abnormalities»
"Behavioral abnormalities" refers to unusual, atypical or abnormal behaviors that are outside the typical or expected range of behaviors exhibited by most people or animals. Full definition
Interestingly, Nav1.1 - deficient interneuron transplants were sufficient to cause behavioral abnormalities in wild - type mice, indicating the key functional role of interneurons and Nav1.1 for cognitive functions.
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Behaviorial Abnormalities (Back to Top) Occasionally hamsters are born with behavioral abnormalities such as repetitive, compulsive circling or back - flipping.
«This is the first demonstration that cells carrying a genetic disease are capable of spreading into the normal mammalian brain and lead to the manifestation of behavioral abnormalities associated with the disease,» says Francesca Cicchetti, professor at the Université Laval Faculty of Medecine and researcher at Centre de recherche du CHU de Québec - Université Laval.
As for the viral theory, prenatal infection has begun to be indicated in the development of behavioral abnormalities and structural differences in the prefrontal cortex.
Baby rats who were anesthetized with ketamine later exhibited difficulties with learning and memory, as well as behavioral abnormalities.
Occasionally hamsters are born with behavioral abnormalities such as repetitive, compulsive circling or back - flipping.
«We propose that after the repair of the leaky gut, neurotoxic molecules do not get into the system and cause behavioral abnormalities,» Mazmanian says.
The more common behavioral abnormalities resulting from stress include:
Remarkably, giving animals injections of lithium salts — which mimics WNT signaling by inhibiting the molecule GSK3 — or giving animals a more specific GSK inhibitor, the researchers were able to restore normal synapse and spine numbers and also improve some of the most significant psychiatric - like behavioral abnormalities in these mice.
«To have an idea of what these genes might do, I searched a database that describes the functions of genes in the mouse and found that mice that have a deletion of the Maged1 gene have neurocognitive behavioral abnormalities.
Additionally, tau reduction ameliorated the learning and memory deficits and behavioral abnormalities present in the Dravet mice, which may relate to the cognitive impairments and autism - like behaviors seen in the human condition.
FTD is known as young - onset dementia and is characterized by behavioral abnormalities including a decline in cognitive, motor, and language function.
In the most common FTD subtype, behavioral variant FTD, patients present with social dysfunction, apathy, disinhibition, repetitive behavior, and other behavioral abnormalities (Rascovsky et al., 2011; Karageorgiou and Miller, 2014).
«Compared to normal animals, these mice have very small brains, and multiple behavioral abnormalities,» says Ferris.
Howard Hughes Medical Institute researchers have produced a genetically altered mouse that exhibits behavioral abnormalities that are strikingly similar to those observed in humans with schizophrenia...
There is no scientific evidence that de-clawing leads to behavioral abnormalities when the behavior of de-clawed cats is compared with that of cats in control groups.
Consumers will often buy kittens based on factors of cuteness and neglect to consider behavioral abnormalities.
Early on she began displaying significant behavioral abnormalities.
Heston also found behavioral abnormalities in many of the other children (Eysenk, 1982).
Francesco Longo is interested in understanding the synaptic and behavioral abnormalities associated with autism spectrum disorder, with particular attention to striatal dysfunction in fragile X syndrome model mice.
Dogs that display any type of behavioral abnormalities, such as excessive shyness, aggression towards dogs or people, tendency to bite, separation anxiety or obsessive - compulsive disorders, probably should not be bred.
Lipkin, the director of the Jerome L. and Dawn Greene Infectious Disease Laboratory at Columbia University, has discovered that susceptible mice react to strep bacteria with behavioral abnormalities: «We took a strain of mouse that is very prone to autoimmunity and exposed the mice to killed strep bacteria, and they developed repetitive behaviors and hyperlocomotion,» says Lipkin.
The virus infects cells of the nervous system, producing incoordination and behavioral abnormalities such as unusual aggression or withdrawal.
VPA has a known link to autism in humans and also induces autism - like cognitive and behavioral abnormalities in mice.
We need to understand how billions of neurons in different parts of the brain talk to each other, and how malfunctions in neural connections get expressed as behavioral abnormalities.»
Now associating ho.mose.xuality with «behavioral abnormalities» seems to be a stretch and I would think that any correlation between gay orientation and «maldevelopment of prefrontal cortical and ventral striatal dopamine systems» would be well docu.mented by now.
I only read the abstract so far, but it seems to be talking about, as you pointed out, «behavioral abnormalities and structural differences in the prefrontal cortex.»
Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.
The offspring did not show most of the behavioral abnormalities, suggesting that epigenetic transmission may not be at the root.
«It is not clear how much we are able to reverse the behavioral abnormalities.»
One of the interesting finding is that a subset of mice or rats that are subjected to these high levels of social stress don't develop these behavioral abnormalities.
This therapeutic strategy not only suppressed seizure activity and premature death, but also improved cognitive and behavioral abnormalities that can accompany this syndrome.
«We hope to advance our research in order to elucidate genetic defects that result in behavioral abnormalities,» Yamamoto said.
When the researchers silenced the genes in the peripheral nerves of adult animals, they were still hypersensitive to light touch, but they didn't display the behavioral abnormalities seen in the animals that had the gene silenced from birth.
«We wanted to find the link between the abnormal structure of synapses in the FXS mouse, and the behavioral abnormalities at the level of brain circuits; that had not been previously established,» said senior author Dr. Carlos Portera - Cailliau, an associate professor in the departments of neurology and neurobiology.
By blending classical and cutting - edge genetic approaches, Vivek Kumar, Ph.D.Researches behavior and behavioral abnormalities, including addiction, ADHD and depression, using mouse genetics as a platform.Vivek Kumar is unveiling the genes at work within the brain to control complex behaviors, such as anxiety and addiction.
Researches behavior and behavioral abnormalities, including addiction, ADHD and depression, using mouse genetics as a...
Neural cognitive deficits and behavioral abnormalities have been noted in Ts65Dn mice.
Dr. Mucke has spent most of his career uncovering the molecular and cellular mechanisms that cause memory loss and behavioral abnormalities in Alzheimer's disease and related conditions.
Inspired by a grandfather who had Alzheimer's disease, Dr. Mucke has spent his career uncovering mechanisms that lead to memory loss and behavioral abnormalities in Alzheimer's and related conditions.
This suggests that NF - kB may be at the center of the behavioral abnormalities observed in FTD.
Mice that are homozygous for the R26 - stop - EYFP mutant allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities.
Increasing EphB2 levels in neurons of mice engineered to produce high levels of human amyloid proteins in the brain prevented their neurotransmission deficits, memory problems and behavioral abnormalities.
Harry Han, Carolyn A. Allen, Christie M. Buchovecky, Michael J. Yetman, Heather A. Born, Miguel A. Marin, Shaefali P. Rodgers, Bryan Song, Hui - Chen Lu, Monica Justice, Frank J. Probst, and Joanna L. Jankowsky (2012) «Strain background influences neurotoxicity and behavioral abnormalities in mice expressing the tetracycline transactivator», Journal of Neuroscience 32:10574 - 10586.
But did you know that many skin, fur, hair, and behavioral abnormalities could be a result of your pet's allergies (or intolerances / sensitivity) to the chow you feed your furry friends?
Behavioral abnormalities: a whole range of abnormal behavior patterns, such as aggression, panic disorders, etc..
The behavioral abnormalities seen in the hyperthyroid cat have been well described in the literature, and mimic closely the restlessness, insomnia and irritability or aggression described in humans with thyrotoxicosis.
Behavioral Abnormalities: A dog behavior evaluation is necessary to examine an aggressive dog, or to determine why dogs are fighting in the home.
A Yorkie with this condition might exhibit some or all of the following symptoms: small stature, poor muscle development, behavioral abnormalities, unresponsiveness, seizures, and so on; however, if treated by a veterinarian, the condition is most often reversible in time.