Biogenesis means the production or creation of living organisms from other living organisms. It shows that life comes from existing life, rather than being formed from non-living materials.
Full definition
Supplementing with BCAAs (Branched - chain amino acids) was also shown to increase
mitochondrial biogenesis in skeletal muscles.
Branched - chain amino acid (BCAA) supplementation increased mitochondrial
biogenesis in skeletal muscle [4].
Next they tested an additional 27 genes that are known to be involved in various steps of
ribosome biogenesis to verify whether SSUP was required for ESC maintenance.
Title: A mitochondrial ferredoxin is essential
for biogenesis of cellular iron - sulfur proteins
This suggested that Zucchini was essential in
piRNA biogenesis, however the molecular underpinnings of its mechanism were still unclear.
In addition to prevent ROS mediated damages SIRT1 promotes mitochondrial
biogenesis by activating peroxisome proliferator - activated receptor coactivator - 1α (PGC - 1α) which upregulates glutathione peroxidase (GPx1), catalase, and manganese SOD (MnSOD) 22.
The 16 transcripts associated with cell wall / membrane /
envelope biogenesis include two putative membrane proteins, two junctional membrane protein complexes, and one transcript with homology to a cell wall surface anchored protein (see electronic supplementary material, table S5).
The Big Bang has nothing to do
with biogenesis and doesn't in any way violate any of the laws of thermodynamics.
Interestingly, IBS biologists uncovered additional miRNA end modifications after DROSHA processing, which are expected to be important for the regulation of
miRNA biogenesis, whose dysregulation is often associated with diseases, in particular with cancer.
Thus, aberrant regulation of
protein biogenesis and topology at the endoplasmic reticulum can result in neurodegeneration.
Human CLP1 mutations alter
tRNA biogenesis, affecting both peripheral and central nervous system function.
Others were unanticipated, including significant differences in expression levels among genes involved in fundamental cellular processes such as
ribosomal biogenesis, transfer RNA processing, and Notch - signaling — part of a complex system of communication that governs basic cellular activities and coordinates cell actions.
He also states that» «anthropic» reasoning fails to distinguish between minimally biophilic universes, in which life is permitted, but only marginally possible, and optimally biophilic universes, in which life flourishes
because biogenesis occurs frequently».
These results not only suggest early mitochondrial
biogenesis deficits as a pathogenic mechanism, but also as a potential biomarker and therapeutic target in individuals with Friedreich's ataxia.
An unexpected ribosome
biogenesis role expands the post ‐ transcriptional gene expression functions of a key bacterial RNA chaperone beyond binding / regulation of small RNAs.
Our studies on the molecular mechanisms of endocytosis led to the discovery that the small GTPase Rab5 is a master regulator of early
endosome biogenesis.
Total β - hexosaminidase content from RhoH + / + and RhoH − / − BMMCs were comparable (data not shown), suggesting that RhoH is dispensable for
granule biogenesis in BMMCs.
The clonal expansion and survival of CSCs seem to be dependent on mitochondrial biogenesis [8, 68 - 71].
Regular postexercise cooling enhances mitochondrial
biogenesis through AMPK and p38 MAPK in human skeletal muscle.
Increasing the number of mitochondria, a process known as mitochondrial
biogenesis takes the demand off of just 10 mitochondria and disperses the total workload among a hundred, which would enable them to do their job of transforming energy from fat into ATP to be used by the body more efficiently.
The biology
term biogenesis = life comes from life really contradicts those who want to believe that life on this earth produced itself.
From the perspective of evolution, adapting to periods of intermittent fasting was one of the driving forces of our
cellular biogenesis.
Excitingly, these proteins are functionally enriched for membrane bending,
vesicular biogenesis, and trafficking activities, suggesting that eukaryotes evolved from an archaeal host that contained some key components that governed the emergence of eukaryotic cellular complexity after endosymbiosis.
They discovered that the 6 RBPs that make up SSUP mediate 18S
rRNA biogenesis in turn making them important regulators for pluripotent cells.
Dr David Lynch, lead author on the study published in Disease Models & Mechanisms, explains that furthering knowledge of the earliest stages of Friedreich's ataxia is essential, as their data suggest that the progressive degeneration in mitochondrial
biogenesis leading to clinical disease is very slow.
This is the first link showing how the cell cycle machinery regulates the trigger of
centriole biogenesis, ensuring the right number of centrioles is formed at the right time, which is critical for homeostasis.»
Although the protein has been involved in telomere and genome instability in the mouse, we have found that it plays an important role in non-coding RNA trafficking and
RNP biogenesis in human cells.
We also investigate the homeostatic mechanisms of
ceramide biogenesis in a microcompartment of the ER and how these mechanisms are integrated in cellular life - death decisions.
In a study led by Hansen's former trainee Dr. Louis Lapierre, now an assistant professor at Brown University, identified a novel link between
lipoprotein biogenesis, autophagy, and aging; this study was published in Autophagy (PMID: 26671266 [PubMed - in process]-RRB-.
While at Heidelberg, he was inspired by the work of Wilhelm Just who was investigating the hotly
debated biogenesis of peroxisomes.
2006 — Ken Keegstra — for his pioneering contributions to our understanding of
chloroplast biogenesis, protein import into chloroplasts, and the structure and biosynthesis of the plant cell wall
Impaired ribosome
biogenesis disrupts the integration between morphogenesis and nuclear duplication during the germination of Aspergillus fumigatus.
We are currently investigating how defects in
centrosome biogenesis can lead to centrosome asymmetry defects.
Phrases with «biogenesis»