Sentences with word «bioinformatic»

The students have undergone a comprehensive education in life science emphasising cutting - edge methods in bioinformatic analysis of big data, high throughput techniques of molecular biology as well as how to translate biological findings into diagnostic tools and novel treatments.

Apart from using a host of cutting - edge molecular techniques such as Next Generation Sequencing or NGS, the researchers also had to develop specific bioinformatic tools for analysing large amounts of genomic data.

Bioinformatics A comparison of bioinformatic approaches for 16S rRNA gene profiling of food bacterial microbiota — Francesca De Filippis — International Journal of Food Microbiology

The basis for this are the so - called «omics» — genomics, transcriptomics, proteomics and metabolomics — combined with new bioinformatic methods for integrated data analysis.

UNISI will perform bioinformatic analysis of RNA sequencing experiments.

Overall, 86.3 % (139/161) of induced genes that have no homology - based evidence for an immune function are either members of multi-gene families, encode proteins shorter than 300 amino acids, encode proteins with bioinformatic evidence for a signal peptide, or have a combination of these properties.

RD - Connect members, often in collaboration with external partners, have developed several bioinformatic tools to help researchers analyse omics data and identify targets for potential therapies.

Most well - characterized effector molecules in other insects are secreted into the hemolymph: in our study, 91.2 % of previously identified AMPs have bioinformatic evidence indicating presence of a signal peptide.

Characterization of the core and accessory genomes of Pseudomonas aeruginosa using bioinformatic tools Spine and AGEnt.

All other proteins were short - listed from bioinformatic analysis of transcription microarray data [38, 39].

The branch serves as a focal point at the NIH campus for the analysis of a wide variety of large - scale genomic data generated in the course of laboratory and clinical studies, with branch members actively involved in efforts aimed at developing new bioinformatic approaches for the analysis and visualization of these data.

• Mouse whole genome scanning The unit offers microsatellite and SNP based Genome Scanning Services for gene identification projects, based on linkage analysis, offering coverage for a number of mouse strains (i.e. C57BL6, DBA2J, CBA, 129S6, 129P2), as well as bioinformatic analysis using suitable mouse genetic software.

Relevant publications: (1) Drug repurposing, computer - based screening (2) Functional testing and novel tools for bioapplications (3) Therapeutic targets and disease pathways by bioinformatic analysis

This requires the development of powerful bioinformatic approaches that allow prediction of haplotypes from numerous variants, and the classification of haplotypes into functionally related categories, in order to identify those specific sequence variants, or combinations of variants, associated with the disease phenotype.

Roughly 2/3 of new studies make use of existing data, either to entirely support computational research, such as bioinformatic algorithm development, or to support and supplement findings from new datasets.

A previous study authored by Millay in 2014 identified myomaker and its gene through bioinformatic analysis.

We conducted bioinformatic analyses of 703...

We have generated rich genomic datasets for the scientific community, including an expansive atlas of genetic associations with metabolites, whole - genome sequence and phenotype data for population cohorts in the UK10K project, as well as bioinformatic resources to facilitate the retrieval of information, including a metabolite network, a database of genotype - metabolite associations with our colleagues at the HelmHoltz institute, and a genome browser of UK10K association results.

As a result, a massive amount of omics data is currently being generated which will be difficult to exploit using solely bioinformatic criteria.

Current strategies for miRNA target identification mainly rely on bioinformatic methods, experimental methods to identify intracellular targets of miRNAs are in high demand.

The development of «bioinformatic packages» for the analysis of genetic variability and genotype - phenotype relationships will be of great value for any basic and applied comparative genomics research issues.

The necessary bioinformatic analyses were performed by experts from the University of Shanghai and from the team of Georg Haberer from the Helmholtz Center Munich.

Turning this data into new science is rapidly increasing the needs for bioinformatic support and efficient management of data.

The enormous amount of data resulting from this multi-omics approach must be converted into useful, comprehensible information by bioinformatic scientists using smart algorithms.

These types of investigations have been enabled by key technologies, including single - cell assays, high - throughput genomic sequencing, and improved bioinformatic algorithms.

DNA sequencing followed by bioinformatic data - crunching revealed the kinds of abnormal DNA methylation patterns typically seen after TET protein loss.

The PhD4MD candidate will integrate a translational investigation team from IDIBAPS, working in strict collaboration with epigenetic bioinformatic experts from the CNAG - CRG.

We will leverage state - of - the - art bioinformatic and biological approaches for investigating how these factors interact in combination to regulate axon growth during RGC development and test the potential of such factors for regenerating RGC axons in a rodent model of optic nerve injury.

Bioinformatic pipeline optimization is needed to better detect resistances conferred by point mutations.

Several bioinformatic teams develop methods for different kinds of applications and support the analysis of large - scale sequencing data:

The user - friendly interface lets users, even without bioinformatic training, analyse Next - Generation Sequencing (NGS) data, such as genomes and exomes, and share them with other researchers.

The Data entre will serve as a knowledge centre for platforms and the Swedish research community, to advise on solutions — whether these are in Sweden or abroad at the international bioinformatic archives.

This work involves molecular - genetic studies in the model flowering plant Arabidopsis thaliana and molecular, biophysical and bioinformatic studies in taxa chosen for their key positions in seed plant phylogeny.

Finally the session and the conference was brought to a close with two bioinformatic project presentations from Leeds students ESR12 Rohit Thakur and ESR13 Joey Mark Diaz.

The INF - project is established to support the demanding bioinformatic requirements of the CRC 1182.

Currently in its fifth year, this 14 - year study relies on the fact that powerful new bioinformatic technologies and discoveries will be developed during the course of the study, and computational analytics will employ these vast networks to create new understanding, diagnostics, and canine cancer treatments.

These predictions have come largely from bioinformatic strategies, involving modeling individual species, groups of species such as «functional types», communities, ecosystems or biomes.

Using a combination of systems biology and bioinformatic techniques, the scientists cleverly isolated proteins, which, when mutated, abolished the plant's ability to respond to CO2 stress.

RD - Connect members, often in collaboration with external partners, have developed several bioinformatic tools to help researchers analyse

Bioinformatic approaches to the analysis of genetic variability and complex genotype - phenotype relationships will moreover include gene sequence and database analyses, measures of association of haplotypes / genotypes with phenotype, clustering procedures, neuronal networks, fuzzy and other techniques in pattern recognition, similarity measures for discrete patterns (e.g., gene sequences, structures, functions), logistic regression methods, and a spectrum of other techniques.

First, samples of leaves from these plants are collected for in vitro cultures to isolate the fungi; then the DNA and RNA of fungi are extracted to sequence them and, through bioinformatic analysis, the researcher can determine the expression, the presence or absence of genes in the genomes of a species against each other.

We conducted bioinformatic analyses of 703 transcriptomes to probe the immune landscape of primary cutaneous melanomas in a population - ascertained cohort.