Sentences with phrase «biologic therapy»

«The British Society for Rheumatology Biologics Register was established in 2001 to monitor the long - term safety of biologic therapies in patients with rheumatoid arthritis.

Better control of inflammation with biologic therapy might reduce not only the rate of heart attacks, but potentially also affect the size of myocardial infarctions.»

There are other, newer biologic therapies available as well.

Cancer immunotherapies also are known as biologic therapy, biotherapy, or biological response modifier therapy, and include cancer vaccines, monoclonal antibodies, and T cell transfer.

Biosimilars» burgeoning popularity has fostered some intriguing partnerships as companies try to create new, innovative biologic therapies, defend their existing products from sales slumps, and develop biosimilars to eat into competitors» branded biologics sales.

«Enzyme keeps antibodies from targeting DNA, driving inflammation in lupus: Study may open door to future biologic therapies.»

Of these, 27 per cent reported non-adherence to biologic therapy according to the defined criteria at least once over the first six - month period.

Faced with an increasing choice of different biologic therapies, rheumatologists have a critical need for better tools to inform their management of RA.

Next, the scientists identified which of these patient populations had joints that were getting better and what biologic therapies they were taking.

Biologic therapy removes the protein molecules being secreted by the macrophages.

Stepping up to biologic therapy when methotrexate monotherapy fails offers minimal incremental benefit over using a combination of drugs known as triple therapy, yet incurs large costs for treating rheumatoid arthritis (RA).

This novel approach may have ramifications for other inflammatory diseases including rheumatoid arthritis and psoriasis, as well as for other biologic therapies (such as Humira) used to treat these conditions.

«Clinical trial designs that test such novel and potentially dangerous biologic therapies should only treat one patient at a time, followed by a reasonable period of time so that adverse events can be monitored,» he says.

However, these results suggest there may exist immunologic scenarios where IFN - γ blockade may not be sufficient to treat HLH and alternative biologic therapies may need to be considered.

The cohort included 9 patients with symptomatic Crohn's disease (CD) and 6 with ulcerative colitis (UC), half of whom were on biologic therapy, with an average disease duration of 19 years (1).

Whilst established to examine possible safety issues with biologic therapies, it provides the opportunity to look at additional benefits beyond the direct effect on disease severity,» explains William Dixon, MD, MRC clinician scientist / senior clinical lecturer and honorary consultant rheumatologist; Arthritis Research UK Epidemiology Unit, The University of Manchester; and an investigator in the study.

Interferon is a type of biologic therapy.

Additional protection for our programs comes from the extensive know how our team has gathered from many years working on these programs, as well as the market protections in place in many countries for new biologic therapies and drugs for orphan conditions.

The med significantly upped the proportion of patients to achieve a 20 response at week 16 when compared with placebo in patients who hadn't yet received a biologic therapy.

The research team evaluated the combination of the biologic therapy brentuximab vedotin (Adcetris), a monoclonal antibody - drug conjugate, with the chemotherapy drug gemcitabine (Gemzar) in 42 pediatric and young - adult patients with Hodgkin lymphoma, the most common cancer in young people ages 15 to 29.

The analysis showed that treating with the biologic therapy first provided marginally more benefits, but an amount that would not be detectable to patients.

The authors cite literature showing this is a strategy that many patients would prefer anyway, since it could reduce their out - of - pocket costs, and would not expose them to the risk of serious side - effects associated with biologic therapy.

Dupilumab, the second new medication, is a biologic therapy given by injection for patients 18 years or older with moderate to severe AD who haven't responded to, or can't use topical medications.

These biologic therapies use an antibody class called immunoglobulin - G (IgG) to bind to and prevent the activity of specific proteins or growth factors.

Clinical trials are studying different combinations of biologic therapy, chemotherapy, steroid therapy, and drugs.

Immunomodulators are a type of biologic therapy.

The antibody targets a peptide on cancer cells, and is a form of biologic therapy, an increasingly appealing alternative to chemotherapy.

Through our prescription medicines, vaccines, biologic therapies and animal health products, we work with customers and operate in more than 140 countries to deliver innovative health solutions.

The chronic leukemias have very effective treatments in the form of biologic therapies (such as Gleevec for CML), which are designed to stimulate the body's immune system to target cancer cells.

More severe cases usually require stronger drugs, such as disease - modifying antirheumatic drugs (DMARDs) and biologic therapy.

• NSAIDs such as ibuprofen (Advil and Motrin) and naproxen (Aleve) • Corticosteroids • DMARDs such as methotrexate (Trexall) and leflunomide (Arava) • Biologic therapies (TNF - alpha blockers) such as adalimumab (Humira), etanercept (Enbrel), and infliximab (Remicade • Immunosuppressants such as cyclosporine (Neoral, Gengraf, Sandimmune) and azathioprine (Imuran)

This role will support Pharmacy services to include conventional and investigational chemotherapy / biologic therapy, Omnicell support and inventory management.