Sentences with phrase «blood stem cells»

With this procedure, adult stem cells, which are also called peripheral blood stem cells, are taken directly from drawn blood.

They are particularly responsible for the self - renewal of blood stem cells.

This method would also enable them to follow potential aging processes that occur in blood stem cells in detail as they occur naturally in a living organism.

Still, scientists are hopeful that someday adult patients will routinely be able to receive cell therapies based on cord blood stem cells.

Both groups isolated carefully characterized blood stem cells from genetically marked mice.

Finally, the researchers cultured them into blood stem cells of the type that could potentially be injected into patients to reverse their disease.

Normally, the bone marrow makes blood stem cells that develop into mature blood cells over time.

He says the structure could also offer a new way of studying blood stem cells and how blood disorders arise.

Scientists have taken a major step forward to making artificial blood by creating blood stem cells in the lab.

The sixth patient included in the report received a booster dose of gene - corrected blood stem cells.

They proved that the absolute oxygen concentration around blood stem cells was indeed low, despite a very large density of the blood vessels.

DNA mutations in bone cells that support blood development can drive leukemia formation in nearby blood stem cells.

The other two sources are bone marrow and peripheral blood stem cells.

Because of the political controversies over embryonic stem cells, information about cord blood stem cells had been unclear.

The new treatment removes more than 98 % of blood stem cells, making it as effective as chemotherapy and radiation.

Blood stem cells in the bone marrow have been labeled with a fluorescent marker protein.

We published the first experience with double autologous peripheral blood stem cell transplant for high - risk neuroblastoma.

To further investigate this hypothesis, the team transplanted fetal mice with blood stem cells from a second strain of mice that were not matched to the fetus or the mother.

Apheresis Unit - Our facility is AABB accredited and one of the few in the United States in which an adult individual can privately collect and store his or her own healthy adult peripheral blood stem cells for use later in life as needed.

Allogeneic Sibling Donor Peripheral Blood Stem Cells Transplantation With Myeloablative Conditioning for Chronic Myeloid Leukemia in Blast Crisis - Successful Treatment Despite Severe Phase of the Disease

A team of researchers at the University of Queensland has developed a new process that has successfully silenced a severe allergic response in mice, using blood stem cells engineered with a gene that can target specific immune cells.

«Protein that keeps blood stem cells healthy as they age identified by researchers.»

«Mechanism vital to keeping blood stem cells functional uncovered.»

A research group at Lund University in Sweden has been able to show that bile acid is transferred from the mother to the fetus via the placenta to enable the fetus to produce blood stem cells.

Mayack and Wagers are the sole authors on the Blood paper, which examines the role of bone cells in regulating blood stem cells.

To explore the potential for application, the group then attempted a similar experiment using human blood stem cells taken from umbilical cords, which they transfected with a vector encoding human Id3.

Essentially, the aim is to genetically alter patients» own blood stem cells so they don't produce abnormal hemoglobin.

Right now, the only cure for some CSAs is a stem cell transplant — the transplantation of normal blood stem cells from another person («donor») to your child.

The treatment had a down side, however: Since 2002, four of 10 children in a French trial for a form of SCID involving a defect on the X chromosome (X-SCID) have developed leukemia, apparently because the retrovirus used to insert a curative gene into patients» blood stem cells turned on a cancer gene (ScienceNOW, 7 March 2005).

In both cases, the mechanisms are similar: the «good» mechanism regulates healthy blood stem cells during an infection, whilst the «bad» one leads to the multiplication of leukemia stem cells.

His current work deploys post-genomic technologies and mathematical modeling approaches to gain further insight into how blood stem cells are configured in molecular terms, the nature of the pathways involved in their cell fate decisions, and how these are corrupted by chimaeric transcription factors associated with human leukaemia.

Several clinics outside the U.S. also offer cord blood stem cell treatments for autism.

The retracted paper, which was cited 13 times, according to theWeb of Scienceonline citation index, describes a series of experiments - including stitching together the circulatory systems of old and young mice - to show that age - related changes in adult blood stem cells can be influenced and even reversed by their environment.

Nine blood stem cell colonies are illustrated in the image, which have developed into differentiated cell types, particularly into white blood cells (leukocytes).

The process of donating peripheral blood stem cells includes taking medication — granulocyte colony - stimulating factor or GCSF — for four or five days, which typically causes five days of slowly building bone and muscle pain, explained Appelbaum.

Jaden's Law would provide for the creation a bone marrow and peripheral blood stem cell donation registry, as well as education and outreach to potential donors.

This fits with studies we've conducted in the past in which we found that the gene primes blood stem cells for leukaemic transformation.»

This image shows the formation of blood stem cells inside the embryonic vessel called dorsal aorta.

Under these conditions, blood stem cells increase the formation of first progenitor cells, which then immediately start supplying new, mature blood cells.

«When we transplanted our labeled blood stem cells from the bone marrow into other mice, only a few stem cells were active in the recipients, and many stem cells were lost,» Rodewald explains.

In the United States, Mackenzie's group and another have embraced a different approach: treating fetuses with blood stem cells culled from their mothers, the strategy she began exploring in animals almost a decade ago.

Systems biologist Prof. Thomas Höfer and colleagues (also of the DKFZ) performed mathematical analysis of these experimental data to provide additional insight into blood stem cell dynamics.

In the bone marrow, blood stem cells give rise to a large variety of mature blood cells via progenitor cells at various stages of maturation.

Several Japanese medical experts want to bank blood stem cells from workers at the ailing Fukushima Daiichi nuclear plant.

Pregnant mother protect growing blood stem cells in the liver of fetus by transporting bile acid.

(The cells would be obtained by giving the workers a drug that nudges blood stem cells from the bone marrow into the bloodstream, then hooking them to a machine that filters out the stem cells.)

For the latest study, a team led by Suzanne Ildstad, director of the University of Louisville's Institute for Cellular Therapeutics in Kentucky, found a way to avoid GvHD by using a regimen involving chemotherapy, radiation and blood stem cells manipulated to eliminate those that cause GvHD while retaining specialized bone - marrow - derived cells they called «facilitating cells».

The problem with making blood stem cells proliferate outside the body is that the artificial growth gives rise to an accumulation of abnormal proteins in a part of the cell called the endoplasmic reticulum, ER.

Researchers at the University of Birmingham have made a breakthrough in understanding how mutated genes in leukemia reprogram blood stem cells and send them spiralling out of control.