Sentences with word «bradykinin»

This caused an excess of bradykinin production, resulting in vessel leakage and swelling.

Nova Technology tried their luck at extending this idea for a group of potential antihypertension drugs known as bradykinin antagonists, based on a short chain of amino acids, A-Arg-B-C-D-W-X-Y-Z-Arg, where each letter represents a different possible amino acid picked from one of nine multiple groups of amino acids.

They found that a protein called GRK2 binds to and prevents delta opioid receptors on rat sensory neurons from responding normally to opioids, but when these peripheral neurons were exposed to a natural inflammatory molecule called bradykinin, GRK2 moved away from the delta opioid receptors, setting off a biochemical reaction that restored the functioning of these receptors.

In hereditary angioedema (HAE), the leakage, and hence the swelling, is primarily caused by the hormone bradykinin.

The 2018 event will focus on contact, kallikrein / kinin, and complement proteins in hereditary angioedema and thrombosis and their developing therapies, kinin receptors in disease, kinin receptor interaction with receptors of the renin - angiotensin system, the influence of the renin angiotensin system with bradykinin and its receptors» biology, and the influence of this overall system in vascular biology, diabetes, hypertension, heart failure and other related disease states.

One is the enzyme bradykinase, which can break down the inflammatory chemical bradykinin when applied topically to skin.

During the early 1970s, a group of researchers in Brazil led by Sergio Henrique Ferreira discovered a family of peptides in the pit viper's venom that increased the activity of bradykinin, a peptide that lowers blood pressure by causing blood vessels to dilate.

It inhibits the release of pain - associated peptides such as bradykinin.

This peptide family, which became known collectively as the bradykinin potentiating factor (BPF), was also found to block the conversion of angiotensin I to angiotensin II, a process that causes blood pressure to rise.

Then he turned his attention to a synthetic analogue of bradykinin, called RMP - 7, that allowed 10 times more chemotherapy to be delivered to the tumor during the 20 - minute window that the blood - brain barrier was open.

In 1993 he found it — bradykinin, a peptide that occurs naturally in the body and could temporarily open only the portion of the blood - brain barrier supplying blood to a feeding tumor.

Comparative effects of immediate - release and extended - release aspirin on basal and bradykinin - stimulated excretion of thromboxane and prostacyclin metabolites.

The KININ meeting occurs every three years, assembling scientists and clinicians involved in the field of bradykinin (kinins) and its related proteins (enzymes, cofactors, substrates, receptors, proteolytic systems, disease states, and developing therapies) for presentation of the latest ideas, research, drug development and therapeutics in these biologic systems.

Potentiation by cholera toxin of bradykinin - induced inositol phosphate production in the osteoblast - like cell line MC3T3 - E1

You may have heard from your physician or other sources terms including but not limited to: leukocytes, macrophages, dendritic cells, mast cells, bradykinin, histamine, and TNF.

The body achieves this by sending numerous chemicals to the wound; these include various cytokines like interleukin - 9, bradykinin (responsible for controlling pain sensitivity), and numerous others.