For this study, Yanik's team developed a new technology to inject RNA
carried by nanoparticles called lipidoids, previously designed by Daniel Anderson, an associate professor of chemical engineering, member of the Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science, and an author of the new paper.
Vassaux's team next plans to test gene therapy carried
by nanoparticles on a variety of tumors in animals.
The binding events localize gold nanoparticles in an electrode gap; silver deposition
facilitated by these nanoparticles bridges the gap and leads to readily measurable conductivity changes.
Indeed, exposure of the protein
produced by the nanoparticle - based gene therapy to the gut mucosa prevents inhibitor development and restores clotting - factor activity in mouse models of both haemophilia A and B. «This approach really could hold big benefit for patients,» says Jörg Schüttrumpf, a transfusion - medicine specialist who led one of the studies performed at the German Red Cross Blood Donor Service in Frankfurt.
The first results from early - stage trials show that cancer drugs
couriered by nanoparticles may reduce the size of tumours in humans.
«Gluing a film to stop leakage» is only one example of the possibilities opened up by adhesion
brought by nanoparticles.
«The barrier is temporary opened at a desired location for approximately 2 hours by a small elevation of the temperature
generated by the nanoparticles when exposed to a radio - frequency field,» explained first author and co-inventor Seyed Nasrollah Tabatabaei.
Using macrophages and a variety of epithelial cell types as models systems, his research employs genomic, proteomic, and cellular imaging approaches, coupled with computational biology strategies to identify the pathways
modulated by nanoparticles and the implications of these pathways for human health.
The results of the project are documented at a paper published at ACS NANO: Solar Vapor Generation Enabled by Nanoparticles
Frank Gu, a professor in the Faculty of Engineering at the University of Waterloo and Canada Research Chair in Nanotechnology Engineering, is the senior researcher on the team that was the first to find that photocatalysis — a chemical reaction that involves the absorption of light
by nanoparticles — can completely eliminate naphthenic acids in oil sands wastewater, and within hours.