Sentences with phrase «candidate disease»
Projects restricted to the creation of conventional mouse knockouts in candidate disease genes identified by association studies, or to broadly overexpress those genes, are discouraged.
mcknight.org
«Our research team is the first to describe a high - throughput in vivo validation system to screen candidate disease genes identified from patients.
This offers a compelling avenue of experimental approaches to functionally validate new candidate disease genes.
Saturday, Oct. 21, 8:30 - 9:30 a.m., Room 220F, South Building Platform Session: Modelling Candidate Disease Variants in Cellular and Animal Models Moderators: Katherina Walz, University of Miami; and Michael Wangler, Baylor College of Medicine
Although hundreds of thousands of samples have been sequenced, our ability to find, associate, and implicate genetic variants and candidate disease genes far outstrips our ability to understand them.
There, Winton's lab has identified «three candidate diseases that we believe are now much worse than they used to be....
Functional validation of a candidate disease gene can also be performed in living cells or organisms.
Purpose.: Previously, we mapped the disease locus in the beagle model of autosomal recessive primary open angle glaucoma (POAG) to a 4 - Mb interval on chromosome 20, and identified a Gly661Arg variant in ADAMTS10 as the candidate disease - causing variant.