Projects restricted to the creation of conventional mouse knockouts in candidate disease genes identified by association studies, or to broadly overexpress those genes, are discouraged. (mcknight.org)
«Our research team is the first to describe a high - throughput in vivo validation system to screen candidate disease genes identified from patients. (sciencedaily.com)
This offers a compelling avenue of experimental approaches to functionally validate new candidate disease genes. (massgenomics.org)