Sentences with phrase «cell fate specification»
Kelly earned her Ph.D. in Cell and Molecular Biology from the University of Pennsylvania studying the role of the EGF - Ras - ERK signaling pathway in cell fate specification.
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Gradients of BMP signaling in zebrafish embryos direct dorsal - ventral cell fate specification during embryogenesis.
Cas is required for polar and stalk cell fate specification, while Eya is a negative regulator of these cells» fate.
Cells are only transiently pluripotent as cell fate specification signals initiate differentiation soon after the formation of pluripotent blastomeres.
Among them, there are genetic instability (mainly aneuploidy, a defect in chromosome number), defects in the symmetry of cell division (important for cell fate specification and tissue architecture) and impaired ciliogenesis.
Although Pdgfrα appears downstream of the fluorescent signal observed here, the dynamic nature of cell fate specification appears similar.
We are also investigating endocytosis of the cell surface receptor, Notch, a protein involved in cell fate specification (6).
We focus on how changes in chromatin structure orchestrate the developmental transitions from fertilization to genome activation to cell fate specification.
The regulation of transcription during the transitions from fertilization to genome activation to cell fate specification is a critical developmental process, yet it is poorly understood.