Sentences with phrase «cellular context»

Every cell type has the same genes, but each gets different instructions to turn on only those needed in a given cellular context.

The advent of high - throughput technologies to systematically evaluate drug effects across different cellular contexts enables such discoveries.

The research of the department focuses on the development of cryo - electron tomography which is widely seen now as a method of unique potential for visualizing macromolecular complexes in their functional cellular context.

HeLa cells maximum intensity projection of 3 - D 2nd order bSOFI of labelled microtubules, color encodes z - position with one slice of the complementing 3 - D phase image providing cellular context.

This is a significant discovery: in many cellular contexts, essential cell fate decisions are associated with an EMT.

The pilot project tested a dozen or so of the most commonly used gene promoters (regions of DNA that facilitate gene transcription) and segments of DNA that encode ribosome - binding sites (sequences of messenger RNA that control protein translation) to determine whether they behave consistently in different cellular contexts.

The Ries group studies nanoscale multi-protein machineries in their functional cellular context, and elucidates their dynamic structural organisation using tailor - made superresolution microscopy technologies.

In defining the cellular context of diffuse midline gliomas, researchers find the cells fueling their growth and suggest a potential approach to treating them: forcing their cells to be more mature.

In this study, the locations of these binding sites were mapped for the first time in a cellular context.

The transgene based on the first construct (covering the upper two isoforms a and c) may lead to the expression of both isoforms a or c fused to GFP dependent on the cellular context and is likely to lead also to overexpression of untagged isoform b from the extra-chromosomal array.

Program investigates strategies to understand disrupted genes and cellular contexts, approaching discovery of drugs with

This dynamic regulation implies that escape from the primary tumor from is very much a non-linear aspect of metastasis that is less influenced by cancer genetics and more by the cellular context, interactions with adjacent tumor cells, the host and response to changing microenvironments.

Many Eph receptors are highly expressed in tumors, but their role in cancer is incompletely understood and likely depends on the cellular context.