Activity in touch - sensitive fibers can actually turn off
shared central neurons, preventing pain signals from reaching the brain.
Several forms of leukodystrophies, genetic degenerative disorders that affect the myelin, are associated with vacuolization of myelin sheaths that enwrap axons
of central neurons.
The serums of some patients with subacute spongiform encephalopathies contain an autoantibody in higher titer against a normal fibrillar protein within the axon of
mature central neurons in culture.
CCHa2 - R expression in the brain is not specific to IPCs but occurs in
other central neurons (Fig 2B, 2C, 2F and 2G).
These images of mouse brains compare laser scanning photostimulation maps of all the neurons connected to one
central neuron in control mice (left) vs. mice dosed with valproic acid (VPA) to induce autism - like symptoms (right).
The central neuron is marked in white, and each colored square represents a neuron that has a direct synaptic connection to the central neuron.