Sentences with word «ceroid»

Some problems found in the Tibetan Terrier are: hip dysplasia (HD), patella luxation, progressive retinal atrophy (PRA), lens luxation (LL / PLL), hypo - thyroidism, cataracts and canine neuronal ceroid lipofuscinosis (CCL / NCL).

OptiGen now offers the CL test for Neuronal Ceroid Lipofuscinosis in Border Collies.

Neuronal Canine Ceroid Lipofuscinosis Basics.

Neuronal Ceroid Lipofuscinoses (NCL) is the general name for a family of at least eight genetically separate neurodegenerative disorders that result from excessive accumulation of lipopigments (lipofuscin) in the body's tissues.

Neuronal ceroid lipofuscinoses are a group of an inherited autosomal recessive metabolic cell storage disorders caused by defective lycosomes, subcellular material that allows enzymes within the cell to process, use and discard unwanted and waste material.

Kittens or adult cats develop anorexia and muscular degeneration; depot fat becomes discolored by brown or orange ceroid pigments.

NCL, sometimes called canine ceroid lipofuscinosis in dogs, is a storage disease; toxins that the body normally would eliminate as waste build up in certain tissues.

Neuronal Canine Ceroid Lipofuscinosis (CCL).

Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.

The drug candidate is intended for the treatment of subjects with neuronal ceroid lipofuscinosis, aka Batten Disease, a fatal lysosomal storage disease that primarily affects the nervous system in children.

In a mouse model of late infantile neuronal ceroid lipofuscinosis (NCL), a pediatric neurological disease, the researchers described retinal degenerative changes that mimic the characteristic pathology of age - related macular degeneration (AMD).

The children all have late infantile neuronal ceroid lipofuscinosis (LINCL), a form of the neurodegenerative disorder Batten disease.

He has been researching juvenile neuronal ceroid lipofuscinosis (Batten disease) since 1997.

The two forms of neurodegeneration are frontotemporal dementia (FTD) and neuronal ceroid lipofuscinosis (NCL).

Common pathobiochemical hallmarks of progranulin - associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis.

For three years now we have been working on human cell models of rare neurodegenerative diseases with special emphasis on neuroacanthocytosis, neuronal ceroid lipofuscinosis as well as motor neuron degeneration (using iPS cells).

Neuronal ceroid lipofuscinosis: a congenital disease where fatty pigments are deposited in the brain and cause brain dysfunction.

Neuronal ceroid lipofuscinosis (NCL) is a rare but serious disease that is limited to show Border Collies.

Canine Ceroid Lipofuscinosis An autosomal recessive disorder of the eyes and nervous system, Canine Ceroid Lipofuscinosis (CCL) causes visual abnormalities that are first noticed when dogs don't see well in dim light.

Dog is a carrier for the Neuronal Ceroid Lipofuscinosis and can pass on a copy of the defective gene to its offspring 50 % of the time..

The genetic test verifies the presence of the Neuronal Ceroid Lipofuscinosis mutation and presents results as one of the following:

There are many forms of Neuronal Ceroid Lipofuscinosis (NCL) result in progressive degeneration of the central nervous system.

In 2005 a nonsense mutation (c. 619C > T) in exon 4 in the canine CLN5 gene was reported to be linked to a specific form of Neuronal Ceroid Lipofuscinosis found in Border Collies.

Animal Genetics offers DNA testing for Neuronal Ceroid Lipofuscinosis NCL.

July 25, 2005 CL (NCL - Neuronal Ceroid Lipofuscinosis) Test for Border Collies The genetic test for Neuronal Ceroid Lipofuscinosis in Border Collies is offered by OptiGen as of July 25, 2005.

Such conditions as neuronal ceroid lipofuscinosis, ichthyosis, kidney disorder, thyroid disorder, cherry eye, hip / elbow dysplasia, entropion and ectropion.

The Border Collie is generally a very hardy and healthy breed, and a responsible breeder will screen breeding stock for health conditions such as hip dysplasia, progressive renal atrophy, deafness, epilepsy, collie eye anomaly, neuronal ceroid lipofuscinosis, and trapped neutrophil syndrome.

Border Collie breeders are usually very proactive in testing for the genetic diseases Collie Eye Anomaly / Choroidal Hypoplasia, Neuronal Ceroid Lipofuscinosis and Trapped Neutrophil Syndrome, but you should check with your breeder before buying a Border Collie on the status of their dogs for genetic diseases.

Neuronal Ceroid Lipofuscinosis (NCL 12) is neurodegenerative disease that affects humans, dogs and other animals (e.g. cattle, sheep, horses).

The Neuronal Ceroid Lipofuscinosis is characterized by accumulation of phospholipids in lysosomes of brain, retina and other tissues.

However, the studies proved that the later onset of retina changes is probably caused by Neuronal Ceroid Lipofuscinosis (NCL) that means completely different genetic disease (Lionel F. Rubin et al. 1995).

P. Gupta, et al., Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice, Proc.

The Neuronal ceroid lipofuscinosis (NCLs) are a group of inherited neurodegenerative diseases characterized by accumulation of autofluorescent cytoplasmic antibodies within cells of the nervous system.

Neuronal Ceroid Lipofuscinosis — Progressive nerve damage that results in weakness of the legs and sometimes blindness.

Infrequently seen diseases include degenerative myelopathy, exercise induced collapse, myasthenia gravis, and neuronal ceroid lipofuscinosis.