The investigations are frequently combined with large scale perturbation methods, including gene - based (RNAi, miss - expression of wild type and mutant genes) and
chemical approaches using small molecule libraries.
Professor Laura Cipolla, from the Department of Biotechnology and Biosciences at the University of Milano - Bicocca, added: «Based on our background on the chemical modification of bio - and nanostructured materials, proteins, and carbohydrates, we designed a new
chemical approach in order to force the organic component polycaprolactone to stay together in a stable way with the inorganic component silica.»
Dr. Sanford is being celebrated for developing
simpler chemical approaches — with less environmental impact — to the synthesis of molecules that have applications ranging from carbon dioxide recycling to drug discovery.
«A huge fraction of the human «proteome» remains uncharacterized, and this paper shows
how chemical approaches can be used to uncover proteins of a given functionality that have eluded classification based on sequence or predicted structure,» said co-senior author Benjamin F. Cravatt, chair of TSRI's Department of Chemical Physiology.
The product, Parasite Dr. Capsules, is worth researching for those owners who want to use a natural
vs. chemical approach to avoiding worm infection.
It may be possible to synthesize a whole family of diamondoid nanothread materials, even with crosslinking between threads, or with added chemical functionality, by
this chemical approach, which is potentially more versatile than difficult - to - control gas - phase approaches.
Their studies could lead to creation of custom designed nanostructures using biological processes that may be more economical and adaptable than mechanical or
chemical approaches.
The yield of plutonium from this «electro - refining» is 10 times that of
the chemical approach used in Europe, says William Hannum, research manager of the project.
Chemical approaches have to be very advanced in order to achieve the same detection thresholds» says Netzer.
The research team found that when a particular mitochondrial fission protein (GTPase dynamin - related protein - 1 — Drp1) was blocked using either gene - therapy or
a chemical approach in experimental models of PD in mice, it reduced both cell death and the deficits in dopamine release — effectively reversing the PD process.
In doing so, they are pursuing various physical, thermal, and
chemical approaches, depending on the material composition.
The improved enzyme gave a 53 % increase in daily production volume and a 19 % reduction in total cost, as compared to
the chemical approach conventionally used to synthesize sitagliptin.
Through the combination of a biological approach using various sugar - digesting enzymes and
a chemical approach using synthetic sugars, the group succeeded in uncovering the active functional site on the plant's sugar chain.
«The induction efficiency of
our chemical approach is comparable the that of the [transcription factor]- induction protocols.»
Dr. Ding, who performed the work described in this paper at The Scripps Research Institute, has pioneered the development and application of innovative
chemical approaches to stem - cell biology and regeneration.
«I hope in the future
the chemical approaches would be more robust in inducing functional mature neurons.»
I do not regret giving in to
the chemical approach.