Sentences with phrase «cholesterol biosynthesis»
"Cholesterol biosynthesis" refers to the natural process in our bodies where cells produce cholesterol. Full definition
HMG - CoA (3 - hydroxy -3-methylglutaryl — coenzyme A) reductase (HMGR) catalyzes the committed step in cholesterol biosynthesis.
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He earned his Ph.D. in biochemistry in 1981, studying cholesterol biosynthesis in the laboratory of James Gaylor.
Defective cholesterol biosynthesis associated with the Smith - Lemli - Opitz syndrome.
By studying the mechanism of hepatocellular carcinoma arising in the setting of nonalcoholic fatty liver disease, Liu et al. discovered a role for squalene epoxidase, a metabolic enzyme involved in cholesterol biosynthesis.
The authors wrote: «We argue that in the era of precision medicine, potential differences in response to compounds that disrupt the cholesterol biosynthesis pathway must be respected, especially as their effect may be defined by both genetic makeup and life events at the same time.»
The extract contains nine different monacolins that inhibit cholesterol biosynthesis in liver cells.