Sentences with phrase «consensus sequence»

Dazl homologs contain slightly different consensus sequences for both RNP2 (VFVGGI) and RNP1 (KGYGFVSF), have distinct sequences surrounding the RNPs, and have a conserved deletion of two amino acids (Figure S2)[35].

Roles of IFN consensus sequence binding protein and PU.1 in regulating IL - 18 gene expression.

Toll - like receptor 9 signaling activates NF - κB through IFN regulatory factor - 8 / IFN consensus sequence binding protein in dendritic cells.

The moxFPs overcome the inherent problems of popular fluorescent proteins and were re-engineered by mutating cysteine residues and N - glycosylation consensus sequences in popular FPs.

In conjunction with the 100 % consensus sequence identity shared among cell line and prostate cancer - associated XMRV genomes (Fig. 6), these findings suggest a high likelihood that a viral contamination event had occurred.

All deviations from the CXCR4 consensus sequence 40 base pairs up or downstream from the ZFN binding site were determined.

This matrix was then aligned to the human genome with the following criteria: putative off - target sites could have up to six mismatches compared to the SELEX consensus sequence, the ZFP pairs must be separated by either 5 or 6 bps, and both ZFP homo - and heterodimers were considered.

Moreover, the recent transposon method identified much higher frequencies of DNA gain events that correspond to full length consensus sequences of known transposon families (Fig 2a and 2b).

Scharton - Kersten, T., Contursi, C., Masumi, A., Sher, A. & Ozato, K. Interferon consensus sequence binding protein - deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction.

Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis.

Based on consensus sequences derived by Drs N Almond and P Kitchin

After sequence read quality and damage filtering (Supplementary Fig. 4), we called per - individual consensus sequences for nucleotide positions covered by a minimum of two independent reads.

The first identified multimeric complex to recognize the ISRE consensus sequence is the IFN - stimulated gene (ISG) factor 3 (ISGF3), which is composed of the phosphorylated forms of signal transducer and activator of transcription (STAT) 1 and STAT2, together with IFN regulatory factor (IRF)-9 (4).

The resulting consensus sequences averaged 16,231 ± 455 bp, or 98.1 % of the complete mitochondrial genome, with the average number of reads per nucleotide position (fold - sequence coverage) ranging from 7.4 × to 117 × among the 9 individuals (Supplementary Data 1).

Additionally, FPs that encode N - glycosylation consensus sequences are modified with the addition of N - glycans [9].

Ko, J., Gendron - Fitzpatrick, A. & Splitter, G. A. Susceptibility of IFN regulatory factor - 1 and IFN consensus sequence binding protein - deficient mice to brucellosis.

Researchers have found that viral protein sequences matching a consensus sequence, which is hypothesized to be most fit, are more likely to be transmitted than those that deviate from the consensus.

For all patients with multiple time points, consensus sequences were identical and iSNV frequencies remained stable (fig.

Interferon (IFN) consensus sequence - binding protein, a transcription factor of the IFN regulatory factor family, regulates immune responses in vivo through control of interleukin 12 expression.

The consensus sequence is GGAAGTGAAA, with the PU.1 - binding core motif (at the 5 ′ end) and the IRF - binding core motif (at the 3 ′ end) underlined.

IRF - 8 / interferon (IFN) consensus sequence - binding protein is involved in Toll - like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN - γ signaling pathways.

The consensus sequence is GAAANNGAAAG / CT / C, where N denotes any nucleotide.

Dots indicate identity with the consensus sequence on the top of the alignment.

When these errors are corrected on the basis of redundant deep sequencing coverage, the final consensus sequences of VP35, VP42, and VP62 are identical to each other and to the 22Rv1 consensus sequence, including a previously described natural polymorphism (A → G) at position 790 [23], [38].