Sentences with word «cytoskeleton»

Role of actin cytoskeleton in cell migration.

These mechanisms are controlled by the activity of cytoskeleton components.

The broad objective of our research is to understand how epithelial cells interact with their microenvironment during migration, focusing on the mechanism of cell migration and the role of actin cytoskeleton in this process.

«The second step involving Akt activation by R - Ras stabilizes the microtubule cytoskeleton in endothelial cells, creating a steady architecture that promotes lumen formation.»

A group of plant biologists at the Institute of Transformative Bio-Molecules (ITbM) of Nagoya University, the University of Tokyo, the Gregor Mendel Institute, and the University of Kentucky, has reported in the journal Proceedings of the National Academy of Sciences, on their discovery on how the plant's egg cells initially lose their skeletal pattern upon fertilization and are reorganized by two major cytoskeleton components in the cell, microtubules (MTs) and actin filaments (F - actin).

This work also includes a protocol for 3D immunofluorescent labeling of endogenous cell cytoskeleton.

This critical structural complex is a protective brace for muscle cells, connecting the cells» internal cytoskeleton with an external surrounding membrane to stabilize the cells and protect them from the stress of contraction.

Expression of brain derived neurotrophic factor, activity - regulated cytoskeleton protein mRNA, and enhancement of adult hippocampal neurogenesis in rats after sub-chronic and chronic treatment with the triple monoamine re-uptake inhibitor tesofensine.

«The absence of sequences closely related to the slowly changing proteins of the eukaryotic cytoskeleton remains unsettling,» Dr. Russell Doolittle of the University of California, San Diego, wrote in the March 26 issue of Nature.

Because as soon as a memory forms, bits of RNA that produce a protein called Arc (activity - regulated cytoskeleton - associated protein) are activated inside neurons for precisely five minutes.

Dr. Kizhatil earned a PhD in microbiology and immunology at the University of Tennessee, Memphis, where he uncovered a new role for the cellular cytoskeleton in murine retrovirus entry.

Cells have support grids called cytoskeletons that give them form and that have functions.

The study reveals that targeting cytoskeleton dynamics could be a previously unexplored strategy to suppress Zika replication.

Also, as the number of knobs increase, the number of linkages between the lipid bilayer and the protein cytoskeleton also increases.

We studied the remodeling of cytoskeleton networks during invadopodia formation and elongation using ultrastructural analysis, spatial distribution of molecular markers, and RNA interference silencing of protein expression.

By tracking single B cell receptor (BCR) molecules we have shown how the cortical cytoskeleton network regulates receptor signalling (Mattila et al. 2013; Treanor et al. 2011; Treanor et al. 2010).

ATIP Avenir program (2015 - 2018): Interplay between cytoskeleton network regulation during muscle development and muscle function.

The researchers reasoned that an organelle would feel less resistance while moving through a more fluid - like, frequently changing cytoskeleton.

The neuronal cytoskeleton regulates the architecture and dynamics of synaptic processes by providing structural support and the tracks for motor protein - based synaptic transport.

The protein triggers the dynamic cytoskeleton within the cell to surround and enclose the bacterium.

The team used a combination of experimental data from live plant cells and computational modeling to gain new insights into how plant cytoskeletons — intricate networks of protein fibers and tubes within cells — cooperate to produce complex cell shapes.

«We are suggesting that, rather than making more of HSF - 1 to prevent diseases like Huntington's, we should be looking for ways to make the actin cytoskeleton better,» Dillin said.

Analysis of differentially expressed proteins revealed enrichment in cytoskeleton organization, mitochondrial activity and ROS management, while gene expression analysis revealed enrichment in the epithelial - to - mesenchymal transition pathway.

2007 Selection of research article, «Duplication and segregation of the actin (MreB) cytoskeleton during the prokaryotic cell cycle,» published in Proceedings of National Academy of Sciences USA, by Faculty of 1000 Biology, which comprehensively and systematically highlights and reviews the most interesting papers published in the biological sciences, based on the recommendations of a faculty of well over 2,300 selected leading researchers.

«Cytoskeleton elements control cellular shape, growth, and movement, provide mechanical support and stress - resilience, and coordinate organelle anchoring and vesicular transport,» says senior author Ralf Bartenschlager, a virologist at Heidelberg University.

Neurobiologist Bernd Knoll at the University of Tubingen in Germany and his collaborators used electron microscopy to picture this neuron's cobweb - like cytoskeleton (its interior scaffolding).

However, many studies of bacterial infection rely upon death of the insect host, or actin cytoskeleton staining of specific host cells, at fixed end - points to look at infection or the mode of action of different bacterial toxins.

Plant cells contain two major cytoskeletons, i.e. microtubules (MTs) and actin filaments (F - actin), which help cells to maintain their shape, provide mechanistic support and enable the cells to divide and move.

Given their in vivo role in pathogenicity, and based on the yeast two - hybrid interaction data, these results point to the importance of these pathogen proteins in modulating host ubiquitination pathways, phagosomal escape, and actin - cytoskeleton rearrangement processes.

Plant cells contain a dynamic cytoskeleton which is responsible for directing cell growth, development, movement, and division.

It also causes cytoskeleton degradation in intestinal cells, contributing to cell death and increased turnover, and decreases levels of heat shock proteins in gut epithelial cells, leaving them more vulnerable to damage.

The search strategy was, I thought, brilliant in its simplicity: read Science and Nature cover to cover each week, highlight anything that sounds interesting (cytoskeleton excluded), and in the meantime skip off to some noncytoskeletal conferences to see what's happening in the rest of academia.

Hartman suggested in 1984 that the nucleus arose when a hypothetical cell that stored its genetic information as RNA instead of DNA and possessed a simple cytoskeleton became the host for an archaeal organism.

Osteoblasts have more cytoskeleton than do adipocytes (fat cells).

Microtubules act as the crucial cytoskeleton, supporting the structure of living cells; as conveyor belts, moving chemical components from one cell to another; and as movers themselves, taking on different formations and dividing chromosomes.

A cell's cytoskeleton serves as a sort of scaffold, made from thousands of proteins that are constantly assembling, disassembling, and reassembling.

Loki has a number of genes typically found in eukaryotes, including genes linked to the dynamic, shape - shifting cytoskeleton.

A cell's cytoskeleton features microtubules, which consist of the protein tubulin assembled into long tubular polymers.

Errington had long suspected that bacteria, or prokaryotic cells, contained cytoskeletons, but even electron microscopy had failed to turn up any evidence.

«The actomyosin cytoskeleton are the main force generator across the animal kingdom,» says Keren.

The gene discovered in the research couples the exocytosis - regulating protein Sec10 with formin, a protein that regulates the remodeling of the actin cytoskeleton critical to forming cell shapes.

In follow - up experiments, Kashina's team found that the γ - actin proteins made from the edited β - actin gene formed a normal cytoskeleton and enabled cell to migrate in a normal fashion.

A fatty, two - dimensional bilayer pairs with a protein - rich cytoskeleton to form the membrane.

Moreover, examination of the role of Mcf1 can be dissected genetically using mutants that either interfere with its endocytosis into target cells, or Rac signalling mutants that hint at early and unexpected Mcf1 mediated effects on the phagocyte cytoskeleton.

«Ghosts» of Mycoplasma mobile — stripped down cytoskeleton covered in the tattered remains of the cell membrane.

The actin cytoskeleton mediates these responses, but the signal transduction pathway leading to chloroplast movement and the mechanism of chloroplast motility is not entirely understood.