Sentences with phrase «differentiation factors»

According to a study published in Science, the protein, called growth differentiation factor 11 (GDF11), can reverse the decline in blood vessel volume seen in the brains of aging mice and enhance neurogenesis (the generation of new nerve cells).

The accumulation of only adult stem cell - like cells indicates a mutation in the master differentiation factor bam completely blocks germline stem cell lineage differentiation.

«In order to carry out the switch from self - renewal to differentiation, Bam must inactivate the functions of self - renewing factors as well as activate the functions of differentiation factors.»

Dr Wael Kafienah, lead author from the University's School of Cellular and Molecular Medicine, said: «We were surprised with this finding, the blend seems to provide complex chemical and mechanical cues that induce stem cell differentiation into preliminary form of chondrocytes without need for biochemical induction using expensive soluble differentiation factors.

«Bam is the master differentiation factor in the Drosophila female GSC system,» says Stowers Investigator Ting Xie, Ph.D., and senior author of the Nature paper.

Our technology enables the identification of potential endoderm differentiation factors, leading to potential discovery of new drugs & agents for research, and, ultimately, therapeutic use.»

In a study published earlier this year, the same Belmonte and Gage lab team demonstrated that a few ES cells in a culture dish tended to lose stemness and evolve into muscle cell precursors, most likely goaded by a muscle differentiation factor known as BMP.

The findings, published in the Proceedings of the National Academy of Sciences, describe how myeloid differentiation factor (MyD88), a protein that plays a major role in mediating host defense response against invading pathogens, is tightly regulated to prevent uncontrolled inflammation.

The main differentiation factor is the richness of the beer; light beer contains 3 - 5 carbs, which is completely safe, while regular and dark / stout / microbrew beers contain up to 15 and 25 carbs respectively.

This is all rumored, mind you, but streaming FiOS access on your Motorola Android tablet would be a huge differentiation factor.

Data and analytics is becoming a resume differentiation factor: Companies are increasingly looking to fill marketing, product management, finance, and other types of jobs with talented professionals who are familiar with data warehouses, analytics, statistical analysis and more.

The study revealed that growth factors — especially one known as growth differentiation factor 9 — coming from the eggs drove the feeding tube multiplication and growth process, acting directly upon the genetic machinery of the follicle cells surrounding the egg.

One of the suspects, growth differentiation factor 11, or GDF - 11, appeared to explain the miraculous heart rejuvenation.

Now, two studies, one led by Fejzo, suggest that an excess of a blood - borne protein, growth differentiation factor 15 (GDF15), is a cause of HG, and perhaps other cases of nausea and vomiting in pregnancy.

The protein, growth differentiation factor 11 (GDF11), was known to regulate stem cell activity; it is abundant in young mice but its level drops as the animals age.

Last year, the protein, called growth differentiation factor 11 (GDF11), was found to have a restorative effect on mouse hearts.

The study, performed in an animal model, was the first to identify growth differentiation factor 10, or GDF10, a molecule that previously had no known role in the adult brain, said Dr. S. Thomas Carmichael, the study's senior author and a professor and vice chair for research and programs in the UCLA department of neurology.

Studying mouse models of glaucoma, Ban, Apte and their colleagues identified a molecule in the eye called growth differentiation factor 15 (GDF15), noting that the levels of the molecule increased as the animals aged and developed optic nerve damage.

In vitro chondrogenesis assays demonstrated that the R206H ACVR1 mutation can stimulate progenitor cells to differentiate to cartilage in concert with the appropriate cell environment and differentiation factors and that this mutant receptor activates BMP signaling constitutively without BMP stimulation.

That stands for growth differentiation factor 11.

One is the molecular identification of cell growth and differentiation factors, and their receptors that mimic embryonic developmental cues, and allow PSCs to differentiate into almost any mammalian cell type.

Scientists found that a molecule known as growth and differentiation factor 10 (GDF10) plays a key role in repair mechanisms following stroke.

Miostatin (also known as growth differentiation factor 8 or GDF - 8), is a myokine produced and released by myocytes that inhibits myogenesis, i.e. growth and differentiation in muscle cells.

The researchers measured the concentration of the protein growth and differentiation factor - associated serum protein - 1 [GASP - 1].

superfamily of secreted growth and differentiation factors, is a negative regulator of skeletal muscle growth.

«Tesla has no differentiation factor between a car that costs $ 150,000 and an entry - level car that comes in the exact same color and has the exact same wheels, interior, and body,» Schaffer says.

Cost is the differentiation factor between different funds.

It was rated 8.8 out of 10 in terms of importance, closely followed by «understanding of the business» (8.6) and «deep specialist expertise» (7.6), in a survey of more than 200 in - house lawyers by Thomson Reuters, Differentiation factor: What do businesses value most from external counsel?