Sentences with phrase «disease onset»

We know that breeders are concerned about the age of disease onset, and the meaning and implications of late onset when making breeding decisions.

Individuals who have type 1 diabetes must take insulin for the rest of their lives after disease onset in order to maintain appropriate blood sugar levels.

In fact, in their study, despite a delayed disease onset, the duration of disease was shortened by lithium administration.

The disease usually begins in a patient's 30s or 40s and, in the decades after disease onset, patients gradually lose the ability to move, talk and even think.

For the study, researchers looked at whether people with neurological symptoms at disease onset were still affected three years later.

The predictive nature of genetic testing poses a risk to the psychological health of children who are at increased risk for disease onset as adults.

This study investigated psychosocial adjustment among adolescents with a chronic illness and examined the role of adolescent disease onset.

This binding causes kidney cells to change their structure and function, permitting disease onset.

Identifying such changes prior to disease onset also may prove useful in determining vulnerability to schizophrenia onset, particularly in those at high risk for the disease, the researchers said.

Many clinical trials have since focused on trying to slow disease onset in these individuals.

«This is critical because the treatments given after disease onset have been unsuccessful,» she says.

Objective To compare psychosocial adjustment among adolescents with a chronic illness to that of healthy adolescents and examine the role of adolescent disease onset.

The complexity of the disease and the lack of a clear familiar tie make screening before disease onset nearly impossible, highlighting the importance of slowing the disease, Dr. Kaspar says.

It's important to note that the measurements described can't be used to predict disease onset for individual people - they only make sense when applied to groups of people, like in a clinical trial.

Verily develops tools and platforms designed to better understand ways to predict and prevent disease onset and prevention.

C Ramirez - Renteria and colleagues conduct a study to evaluate the molecular abnormalities in the AIP gene in a cohort of Mexican patients with acromegaly with disease onset before the age of 30.

«To our knowledge, this is the first direct evidence that Akt1 causes disease onset and progression of pulmonary fibrosis and pulmonary hypertension,» Shenoy said.

In an accompanying editorial, Steven J. Keteyian, Ph.D., and Clinton A. Brawner, Ph.D., of the Division of Cardiovascular Medicine at Henry Ford Hospital in Detroit, wrote, «We are reminded that we still know relatively little about how variations in physical activity and exercise «dose» might impact disease onset.»

People at risk for Huntington's Disease are interested in research which suggests how to live a healthy lifestyle that postpones disease onset as long as possible.

She said new statistical advances will enable scientists to perform other forms of microbiome research such as identifying microbial species and genes that are biomarkers for disease onset or conducting drug development that targets the microbiome.

When mutant genes in only the microglia were silenced, the scientists found almost no effect on disease onset, however the disease progression was significantly slowed.

Mortality and disease onset trends have played out more favorably for dementia, however.

In the group who had no symptoms at the start of the study, the level of neurofilament predicted subsequent disease onset, as volunteers with high neurofilament levels in the blood at the start were more likely to develop symptoms in the following three years.

«The underlying cause of psoriasis remains unknown, and the specific signals that trigger disease onset are still being investigated.

SIGMAR1 deficiency accelerated disease onset of SOD1 - ALS mice by more than 20 %.

This is a key finding that suggests disease onset outside of alveolar macrophages is not only possible, but also important in the pathogenesis of tuberculosis infection.»

Changes in children's gut microbes could signal the onset of type - 1 diabetes, but engineered probiotic bacteria could help treat the disease

«The most interesting finding was that the levels of the microRNAs begin to increase many years before the individual shows symptoms and continue to increase as disease onset approaches.

«We need to reevaluate our understanding of the causes and signals that regulate disease onset and progression, and recognize that neurological disorders can not be described in isolation,» Akassoglou said.

Dec. 1, 2017 — Recent findings suggest that vitamin C deficiency could contribute to Alzheimer's disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset.

There are at least three unique challenges hampering brain disease management: relative inaccessibility, disease onset often preceding the onset of clinical symptoms by many years and overlap between clinical and pathological symptoms that makes accurate disease identification often difficult.

It takes many years to develop following the inhalation of asbestos fibres, but is usually rapidly fatal following disease onset.

Disease onset during adolescence has been neglected but may have important implications for adjustment.

In a particularly important study, researchers correlated antibiotic use in children, changes in microbiota, and adult disease onset as a result of dysbiosis.

One candidate proposed by AI machines recently produced promising results in preventing the death of motor neurone cells and delaying disease onset in preclinical tests in Sheffield.

An increased amount of miRNA in brain cells was correlated with a younger age at disease onset and an earlier age at death of the patients.

Toxic amyloid - beta molecules start accumulating in the patients» body 15 - 20 years before disease onset.

Specifically, Amy is alerted to her particularly high risk of developing type 2 diabetes, and her physician recommends a rigorous program of diet and exercise that had been shown in a controlled study to delay or prevent disease onset.

«We have uncovered a novel control that makes definitive decisions about whether a retina or brain cell will survive or die when threatened with disease onset.

In 1994, he introduced the term «vulnerable plaque» to describe those plaques likely to disrupt and cause disease onset.

«We are learning that the lung microbiome potentially plays a role in many parts of the body including cord blood cells, which may impact disease onset or symptoms.»

«Possible biomarker for Huntington's disease: May result in postponing disease onset.»

In the mouse model of MS, experimental autoimmune encephalomyelitis (EAE), positive effects of modified fasting and ketogenic nutrition on disease onset and clinical course in animals have been observed in several studies.

«This shows that brain cells are capable of responding even after disease onset, and hints at the potential for reversing Huntington's disease.»

We usually define a biomarker as a test that can predict disease onset, progression, or success of treatment.

Protein biomarker discovery for disease onset and progression, drug treatment and toxicity using mass spectrometry and array - based techniques

«At this stage, it is unclear whether these patterns will be reflected in actual rates of disease onset as the cohort is still relatively young.

Without an invasive valve replacement surgery, most patients will die within two years of disease onset.