Sentences with phrase «donor stem»

This study is exploring how to improve bone marrow transplant procedures so the body better accepts donor stem cells.

The disease can occur in patients who have received donor stem cells or immune.

These hosts have hematolymphoid systems that are derived wholly or in part from donor stem cells.

He said this kind of add - on therapy will promote the wide - spread application of donor stem cell transplants as a curative therapy for hematological malignancies like leukemia and lymphoma, without the nasty side effects that often come along with transplantation.

Abatacept, when added to the standard drug regimen used to prevent GvHD, reduced the occurrence of acute, grade III - IV GvHD from 32 to 3 percent in pediatric and adult patients who underwent mismatched unrelated donor stem cell transplants to treat advanced cancer and other blood disorders.

Alix Berglund's research, funded through a grant from the Morris Animal Foundation since 2016, is centered on making donor stem cells more reliable in equine therapy...

An engineered bone that has its own marrow can encourage donor stem cells to produce blood, a feat that could help people with anaemia and rare immune diseases

«Right now the problem in donor stem cell therapy is that we inject the stem cells into the patient but most of the stem cells don't proliferate very well, so they repair very little part of the muscle,» Kumar said.

Tamping down a patient's immune system, they theorized, would give donor stem cells and their progeny a chance to outcompete the patient's existing cells with a minimal risk of rejection.

«Using donor stem cells to treat spinal cord injury: Immune cells populating spinal cord after injury affect ability of stem cells to promote recovery.»

The approach, which is described in a paper to be published September 7 in The Journal of Experimental Medicine, could allow those in need of such transplants, including leukemia and lymphoma patients, to be treated with fewer donor stem cells while limiting potential adverse side effects.

Most donor stem cells are collected through a process called leukapheresis.

In the future, outpatient blood and bone marrow stem cell transplantation will be offered to a broader group of patients with other blood disorders and for allogeneic transplants (transplant from non-twin donor stem cells).

Procedures include purging of cancerous cells and purifying donor stem cells to minimize graft - versus - host disease (a serious side effect related to the use of donor cells for transplant).

Though heroic educators and generous donors stemmed the tide in many places, even creating exemplars of what was possible, forecasts were bleak.

Her project funded by the Morris Animal Foundation will examine if a new type of cell culture treatment can prevent an immune system from rejecting donor stem cells, improving a horse's chances of recovery from a potentially fatal injury.

Examples include a series of studies to document persistent microchimerism of donor cells in transfusion recipients, with particular focus on mechanisms and clinical relevance of donor stem cell microchimerism in transfused trauma patients, and the immunological mechanisms and prevention of transfusion - related acute lung injury (TRALI) and alloimmunization.

Berglund's research, funded through a grant from the Morris Animal Foundation since 2016, is centered on making donor stem cells more reliable in equine therapy.

Given the challenges of transplanting donor stem cells, such as the possibility of rejection by the recipient, researchers are especially interested in finding ways to use stem cells already living in the body.

Blood cells made by the donor stem cells inside the implant were able to get into circulation where they mixed with the host's own blood cells.

Effector T cells incite GvHD when they become overactive as the patient's immune system starts to rebuild itself from the donor stem cells.

Graft - versus - host disease is a condition in which the patient's immune system is attacked by the donor stem cells.

Donor stem cells are transplanted to a recipient, but not without the risk of developing GVHD, a life - threatening complication and major cause of death after SCT.

HSC death is a particular problem if the number of donor stem cells is low to begin with.

For individuals with a known genetic link to autism, Kurtzberg expects that donor stem cells — which presumably will not have the mutations that might have caused autism — are more likely to treat the condition than the individuals» own banked cells.

The new immune system that grows from the donor stem cells can recognize myeloma cells as «foreign» and kill them, which is known as the «graft - vs - myeloma» effect.

In the research, analysis was conducted on more than 10,000 unrelated donor stem cell transplants which took place between 1999 and 2014, where the donor and patient were HLA - matched.

His research interest is graft - versus - host disease (GVHD), an immune complication after a donor stem cell transplant.

His research interest is graft - versus - host disease, an immune complication after a donor stem cell transplant.

UK About Blog Unfortunately his treatment didn't work and he is now having a brand new type of drug in the hope of having a donor stem cell transplant later this year.