Sentences with phrase «efficacy of these drugs»

Finally, we know that treatment early in the disease course is associated with improved efficacy of drugs and better outcomes, such as reduced risk for surgery.

Pharmacogenomics — the study of how genes affect responses to drugs — is becoming more important in drug - development research and clinical trials, with a view toward decreasing side effects and increasing the efficiency and efficacy of drugs in patients with the right genetic profiles.

Eye and Ear soon to determine efficacy of the drug for this indication.

The long - term efficacy of drug treatments is unknown in terms of the accumulation of disability and the prognosis of relapsing - remitting MS.. A better understanding of the neuroprotective effects of available drugs and newer compounds is needed,» the authors conclude.

In the argument for the spiritual efficacy of drugs, much is made of feeling or failing to feel God's presence.

Phase 3, the next step envisaged by Professor Gabay's team together with AB2 Bio Ltd., will aim to assess the actual efficacy of the drug.

Finding ways to deliver and release anticancer drugs in a controlled manner that only hits the tumor can greatly reduce the amount of side effects from treatment, and also greatly increase the cancer - killing efficacy of the drugs.

• Recent research has revealed a reduced efficacy of drugs when they are administered covertly to the patient.

BOSTON, Mass. — Emulate, Inc. announced today that it has formed a strategic partnership with F Hoffman La - Roche AG (Roche) that will use Emulate's Human Emulation System across R&D programs to enable more human - relevant studies that will lead to earlier and better prediction of safety and efficacy of drug candidates.

Do not take Dandelion without talking to your doctor first if you are taking certain medicines used to treat infection (antibiotics such as Cipro, Tequin, Levaquin, etc., as it may lower efficacy of drug); Potassium supplements for health condition (too much may be harmful); Blood thinning medicine (Coumadin, Plavix, aspirin, etc.).

The agency ordered the commercial pulled after just a few days because it was «false and misleading,» «overstates the efficacy of the drug product» and «may result in serious consequences, including death.»

«This phase III trial will be noteworthy for being the first prostate cancer trial to assess a biomarker, namely AR - V7 in circulating tumour cells, as a predictor of response at the same time as testing the efficacy of the drug,» Prof Taplin will conclude.

PIB is not only a powerful tool for studying the efficacy of these drugs; it is also a way to ensure that patients on the road to Alzheimer's start getting treated early enough to minimize irreparable neuronal loss.

Such randomized controlled trials have long been unmatched as a way to determine the safety and efficacy of drugs and other treatments.

The only remaining need for the live virus was to test the efficacy of drugs in vitro, it said.

«Given the cost and potential side effects associated with pregabalin, it is critical that we understand the efficacy of this drug,» Markman said.

To find the answers, further study on this difference will be needed to gain a better understanding of susceptibility to disease, efficacy of drugs and even the course of normal development among all individuals, not just between men and women.

Neurologist Malcolm MacLeod of the Centre for Clinical Brain Sciences at the University of Edinburgh and his colleagues combed through papers reporting the efficacy of drugs in eight animal disease models and checked whether the authors reported four measures that are widely acknowledged to reduce the risk of bias.

The organs - on - chips can then be used to test the efficacy of drug treatments on a particular organ.

Chimeras can provide better ways to test the efficacy of drugs and vaccines than existing methods, says Carrie Wolinetz, an NIH policy official.

Some geochemists even hope that, as techniques improve, there could be applications in diagnosing diseases and measuring the efficacy of drugs on individuals.

In broad terms, a regulatory writer assists in the production of the clinical documentation required by these national regulatory agencies when assessing the safety and efficacy of drugs.

To this day, some drugs remain on the market despite the FDA having no additional scientific evidence to back up the safety and efficacy of these drugs.

Theoretically, it may be possible to enhance the efficacy of these drugs based on our findings, but if so it's in the future.»

To address these issues and improve the quality of Accelerated Approval confirmatory studies, Kesselheim suggests that the FDA clearly describe the limitations in the pre-approval data that will need to be addressed in post-approval studies and that they work with manufacturers to ensure that post-approval studies are conducted using design features that will be optimally useful for confirming the efficacy of the drug.

DACA's arbitrary enrollment criteria, which only allow immigrants born after 15 June 1981 to apply, created control and treatment groups similar to those used to test the efficacy of drugs in clinical trials.

During that time, the FDA granted 22 drugs Accelerated Approval and ordered 38 post-approval studies to confirm the safety and efficacy of these drugs.

«In any event, the outlook for the efficacy of drugs in brown adipose tissue can be adjusted upwards,» said the researcher.

«We're not just interested in predicting the efficacy of a drug, but its side effects as well,» said Bernhard Palsson, the Galetti Professor of Bioengineering at the Jacobs School of Engineering at UC San Diego.

The trial is testing the efficacy of a drug combination in children with the premature ageing disease progeria.

This will generate real models not just for genetically based brain diseases, but also cancer, immune, or metabolic disorders and allow us to test the efficacy of the drugs for these conditions before clinical use.»

It will be interesting to assess whether the efficacy of these drugs can be linked, at least partly, to restoration of FES expression.

Replenishing these microbes in both sets of mice restored the efficacy of the drug.

As is the case with all experimental cancer drugs, Onyx - 015 still must be evaluated in a phase III trial, a much larger trial designed to test the efficacy of a drug in a large population.

In addition, the knowledge must be imparted to scientists studying the efficacy of drugs on a variety of diseases that may be affected by compounds in soy.

This model allows senescent cells to be eliminated due to a genetic manipulation, and will be a «gold standard» against which to judge the efficacy of drugs that hopefully do the same.

Exposure to atrazine while taking aromatase inhibitors for treatment of breast cancer could decrease the efficacy of the drug.

Whereas drug companies have to prove the safety and efficacy of a drug, with supplements the FDA bears the burden of proof that a supplement is unsafe or adulterated.

We need those clinical and field trials in the shelter environment... to determine the safety and efficacy of this drug.»

This group was to demonstrate the efficacy of this drug in preventing heartworm infections; its high efficacy was clearly demonstrated.

For this reason, experts point out that the efficacy of these drugs is noticeable specifically in dogs with osteoarthritis.

The Canine Spinal Cord Injury Program at North Carolina State University's Veterinary Teaching Hospital is evaluating the efficacy of a drug being developed to improve hind limb function in chronically paralyzed dogs.

Weissman, M.M., Prusoff, B.A., Dimascio, A., Neu, C., Goklaney, M., Klerman, G.L., The efficacy of drugs and psychotherapy in the treatment of acute depressive episodes.