Sentences with word «embryonal»

But the average age of embryonal rhabdomyosarcoma is 8.2 years.

When researchers screened a library of more than 200 drugs and related compounds for activity against embryonal subtype tumor cells from three patients, the most promising results involved drugs that increased oxidative stress in tumor cells.

Manjila S, Ray A, Hu Y, Cai DX, Cohen ML, Cohen AR: Embryonal tumor with abundant neuropil and true rosettes (ETANTR): two illustrative cases and review of the literature.

Funding Agency K99 / R00 National Institutes of Health (NCI) Title A role for Notch in self - renewal in Embryonal Rhabdomyosarcoma.

Embryonal carcinoma (EC) cell lines are models for early cells in mouse embryogenesis.

Status Active Active Period 2014 - 2019 Role Principal Investigator Grant Detail The major goal of this project is to determine the effects of misregulation of Notch signaling pathway on relapse or tumor propagating cell self - renewal in Embryonal Rhabdomyosarcoma.

For p53 and p73, the positive control was human embryonal kidney cell line 293 (BD Pharmingen, San Diego, CA).

Lysates from human embryonal kidney (HEK) 293T cells transfected with or without the precursor for miR - 142 or miR - 150 were immunopurified using an anti-Ago antibody.

In another case a 4 - month old dog was affected with embryonal rhabdomyosarcoma of the trachea.

In this study, 58 percent of patients with intermediate or high - risk embryonal subtype tumors had mutations in genes, including NRAS, KRAS and HRAS, that make up the RAS pathway.

The signaling pathway is essential for embryonal development and also plays a pivotal role in the development of cancer or physical malformations.

The study focused on embryonal rhabdomyosarcoma caused by mutations in the Sonic Hedgehog signaling pathway and used a mouse model developed in Hatley's laboratory.

Research led by Mark Hatley, MD, PhD, of St. Jude Oncology, has shown that certain embryonal rhabdomyosarcoma tumors arise from early endothelial cells instead.

Beckwith - Wiedemann syndrome (BWS) is a disorder of prenatal overgrowth and affected patients frequently have embryonal malignancies such as Wilms» tumor (WT).

A biopsy of the removed mass concluded the infant had embryonal hepatoblastoma, which is more aggressive than fetal hepatoblastoma.

They typically lie close to embryonal lines of closure.

Kristine Hill, Ross University in St. Kitts, is conducting a survey of late - stage embryonal deaths in leatherback sea turtles, now considered a vulnerable species.

Cross-species array comparative genomic hybridization identifies novel oncogenic events in zebrafish and human embryonal rhabdomyosarcoma.

In vivo imaging of tumor - propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma.

Glycogen synthase kinase 3 inhibitors induce the canonical WNT / β - catenin pathway to suppress growth and self - renewal in embryonal rhabdomyosarcoma.

RAS pathway mutations were not the only changes that distinguished the normal and embryonal tumor genomes.

About 60 percent of rhabdomyosarcoma patients have tumors of the embryonal subtype, and about 25 percent have the alveolar subtype.

Embryonal rhabdomyosarcoma included far more genomic alterations than alveolar subtype tumors.

As Gurwitsch hypothesized: «The place of the embryonal formative process is a field, the boundaries of which, in general, do not coincide with those of the embryo but surpass them.»

Abstract Neuroblastoma is an embryonal neoplasm arising from the peripheral nervous system that accounts for 15 % of cancer deaths in childhood.

Nearly 150 years ago, Julius Cohnheim first proposed the CSC hypothesis (also called the «embryonal - rest theory») that suggested the presence of embryonic - like cancerous cell remnants in adult tissues that can develop into cancer in a non-spontaneous way (1).

Pineal region tumors: This group of tumors includes germ cell tumors, germinomas, non-germinomatous germ cell tumors, embryonal cell tumor, yolk sac tumors, teratomas (immature vs. mature), pinealoblastomas, and pineocytomas.

Embryonal Rhabdomyosarcoma - Embryonal rhabdomyosarcoma is the most common type of rhabdomyosarcoma reported in dogs.