Sentences with phrase «fibril formation»
The results pinpoint a critical intermediate step in the chemical pathway that leads to amyloid fibril formation.
sciencedaily.com
«Taking a drug to promote fibril formation could be one way to reduce toxicity in SOD1 - ALS,» Dokholyan said.
Products from an early stage of fibril formation were even more toxic to cells than the final, fibrillar form — just as some researchers suspect is the case for early stages of protein misfolding in Alzheimer's disease.
The symposium will summarize new aspects of tooth enamel production, collagen fibrils formation, the role of glycosaminoglycans and their interaction with proteins, and the tissue engineering of cartilage and bone.
These findings indicate that amylin fibril formation in the pancreas may cause islet cell dysfunction and death in type - 2 diabetes mellitus.
University of Wisconsin - Madison professor Martin Zanni used a sophisticated technique that relies on 2 - D infrared spectroscopy to follow the sequence of events in the chemical reactions leading to fibril formation.