Her research achievements helped advance the development and application of human relevant in vitro
models for drug discovery.
The potential for this to be useful was obvious — both in understanding the molecular and cellular biology of the disease, but
also for drug discovery and screening.
This approach will allow in - depth study of these diseases and may serve as a valuable
system for drug discovery and screening.
They promised to pump # 300 million into basic science, create a separate
fund for drug discovery and establish an international dementia institute.
A global consortium of HD researchers has just published a landmark study of genetic differences between people that might explain some of that variability, producing some tantalizing new
targets for drug discovery efforts.
He has developed paradigms that are being used to screen drugs that enhance social function, and is developing novel
strategies for drug discovery for treating social impairments in autism and schizophrenia.
Lewis's method of digging around the dirt for drugs has already yielded several other promising microorganisms, including a potential cancer drug — so it's likely that the research team has unlocked a great new
resource for drug discoveries.
«This is very good news
for drug discovery since the scientists at CBCS have such great knowledge of assay automation in general and CETSA in particular» said
«It's a profound idea,» says Mukund Chorghade, president of THINQ Pharma in Mumbai, India, who believes it would be a
boon for drug discovery because it could provide untold numbers of lead compounds for developing new treatments.
The Cancer Prevention and Research Institute of Texas (CPRIT) became embroiled in controversy last spring when its oversight committee, after a brief review by business experts, approved a $ 20 million incubator grant mostly
for a drug discovery center at the University of Texas (UT) MD Anderson Cancer Center in Houston.
«The time frame for ESCs is
now for drug discovery, soon for personalized medicine, and decades for therapeutic use.»
Dr. Yamanaka's iPS discovery, first completed with animal cells in 2006 and with human cells in 2007, has since altered the fields of cell biology and stem cell research — opening promising new
prospects for drug discovery, personalized medicine and tissue regeneration.
Points to novel
pathway for drug discovery, will be incorporated into tests to improve screening and early detection of abdominal aortic aneurysm, heart attack and PAD Reykjavik, ICELAND, 11 July 2010 — Scientists at deCODE genetics and academic colleagues from the...
As the cost of sequencing plummeted in sync with the rise of computer processing power, Harper saw an undervalued
asset for drug discovery: Amgen bought the company in 2012 for $ 415 million.
Tracing genes of known function and comparing how they are related to unknown genes helps one to predict unknown gene function, which is
foundational for drug discovery and Epidemiology.
New York State was planning to invest in a new facility in
Buffalo for a drug discovery company, Albany Molecular Research Inc., and the medical campus was being invited to partner.
«They said, «All these biomarkers and things we thought were going to be so
productive for our drug discovery process and discovering new targets — now we're drowning in targets and having the same old problems with drugs failing,»» Omenn says.
«The study findings represent a very major advancement in therapeutic target identification for ccRCC and open new
avenues for drug discovery and development.
The ability to start from cellular scratch using non-muscle tissue will allow scientists to grow far more muscle cells, provide an easier path to genome editing and cellular therapies, and develop individually tailored models of rare muscle
diseases for drug discovery and basic biology studies.
But, although modern technologies are accelerating the number of compounds that companies can produce and analyse, in Canada there has not been a dramatic increase in the number of jobs
created for drug discovery scientists.
Working on the premise that scientific research is the foundation of any technology industry, Hancock and others at UBC are writing a business proposal for an integrative centre for drug research, with an objective of developing intellectual property in drug discovery, providing
training for drug discovery researchers, and developing new technologies.
Hooker and Van de Bittner note, however, that the tool also has tremendous potential for research applications,
particularly for drug discovery in smell - loss therapy and in understanding the relationships between olfactory neuron health and brain health more generally.
Attrition of novel drug candidates due to cardiovascular liabilities (including proarrhythmic risk due to delayed ventricular repolarization and Torsades - de-Pointes arrhythmia) remains a
hurdle for drug discovery efforts, a hurdle which may be mitigated by the use of human induced pluripotent stem - cell derived (hiPSC)- cardiomyocytes.
To identify genes that might be
relevant for drug discovery, the investigators plumbed DNA data from patients with coronary disease and from healthy controls.
The researchers believe that their combination of single - molecule fluorescence spectroscopy detection and their computational models offers a novel
route for drug discovery.
«Coming back to China gave huge opportunities,
especially for drug discovery,» says Zhu, who completed postdoctoral training at the Institute of Pharmacology at Germany's University of Kiel.