Basically, scientists could put a cat's tumor in a mouse used
for human cancer research — but why would drug companies focused on human cancer want them?
A controversial weed killer may inadvertently act as a
fertilizer for human cancer cells — and scientists are closer to understanding how.
But Colletta says injections of TGF beta - 1 are unlikely to prove an appropriate
treatment for human cancers because of possible side effects.
He has chaired numerous NIH committees and served on the National Advisory Council for Human Genome Research and the NCI Mouce
Models for Human Cancer Consortium.
Here's a little insight from the medical profession on COX: «The increase of evidence implicating COX - 2 in cancer has stimulated clinical trials to investigate the efficacy of selective COX - 2 inhibitors in individuals at
risk for human cancer.
Canine malignancies that have been established as strong comparative models (17)
for human cancers include transitional cell carcinoma of the bladder (17), non-Hodgkin's lymphoma (18, 19) and leukemia, osteosarcoma (20), melanoma (particularly oral melanoma; refs.
«The LSC17 score is the most powerful predictive and prognostic biomarker currently available for AML, and is the first stem cell - based biomarker developed in this
way for any human cancer,» says Dr. Wang.
Now researchers working on canine cancer have an authenticated resource similar to what's
available for human cancers,» says Daniel L. Gustafson, PhD, CU Cancer Center investigator and director for basic research at the Flint Animal Cancer Center.
Importantly, the interaction networks formed between these proteins occur within regions that are highly similar to the human complex, suggesting the complexes are comparable and making this research highly relevant to understanding the molecular
basis for human cancer.
Scientist Reprogram Cancer Cells With Epigenetic Drugs Researchers at the Johns Hopkins Kimmel Cancer Center have breathed possible new life into two drugs once considered too
toxic for human cancer treatment.
Over the past 18 years, the section has been involved in the discovery of several genetic risk
loci for human cancers, including our evidence that rare DNA variants in the RNASEL and HOXB13 genes strongly increase the risk of prostate cancer and that RGS17 is a gene that acts in conjunction with cigarette smoking to influence lung cancer risk.
Dr. Kemp leads a program in functional genomics to identify new therapeutic
targets for human cancer, supported largely by a U01 grant in the Cancer Target Discovery and Development Network.
The Noma laboratory seeks to determine evolutionarily conserved 3D genome - organizing mechanisms and their functions in the yeast model as well as in the human system, and also establish a clear mechanistic framework for understanding the molecular
underpinnings for human cancers related to the disorganization of the cell nucleus.
«The tumors with potential
relevance for human cancer biology include osteosarcoma, mammary carcinoma, oral melanoma, oral squamous cell carcinoma, nasal tumors, lung carcinoma, soft tissue sarcomas, and malignant non-Hodgkin's lymphoma.»
The research parallels that
done for human cancer treatment and is showing good results in shrinking soft tissue sarcomas with few side effects, according to a report from scientists at Heska Corporation2.
«Being a cancer researcher myself, I saw the value for my dog as a potential, but I also saw the value for other people's dogs, and
for human cancer patients,» Ted said.
Those who feel there is something «unnatural» about introducing human genes into animals or plants forget that we share a high proportion of our genes with these species already: it is precisely this collective heritage that allows experiments on frogs to spawn
treatments for human cancer.
Steve's hope is that in addition to its more practical functions, it will act as a community hub, where anyone working on glioma can get the information and datasets they needed to get a project underway: «The zebrafish, mouse and fly communities have these kind of databases and repositories and we should be thinking about
them for human cancers as well — making it more like a model system.»