But brain cells that had been created using the direct conversion technique had different patterns of gene expression depending on whether they were
created from young donors or older adults.
A biotech startup called Alkahest, spun out from a Stanford lab, reported results in November from a placebo - controlled safety trial testing the effect of
plasma from young donors on 18 patients with mild to moderate Alzheimer's.
Increasing the expression of one of the proteins, SIX3, in the insulin - producing cells
isolated from younger donors enhanced their ability to respond efficiently to rising glucose levels.
He did, however, publish a paper last year documenting a study in which he infused three cancer patients with white blood cells
from young donors who had been injected with G - CSF.
Your article on transfusions of blood
from young donors possibly reversing senility (20 October, p 10) sparked a long - forgotten memory...
Should transfusions
from young donors turn out to be effective, it would be difficult to scale this up as a treatment for all.
The event is the group's annual fundraiser to gather donations and
support from younger donors, and many local Atlanta restaurants donate small bites at the event.
This is the first study to suggest that red blood cell
transfusions from young donors and from female donors may be associated with poorer survival in recipients.
Some teams have begun giving
plasma from young donors to older people, to see if it can improve health (see «Fetch the young blood «-RRB-.
His group has started a company that is planning a small clinical trial that would give Alzheimer's patients a series of injections of plasma
from young donors.
Sharon Sha presented findings Nov. 4 from a small clinical trial that found administering blood plasma
from young donors to people with mild to moderate Alzheimer's disease was safe.