Sentences with phrase «glucose transporters»
"Glucose transporters" refers to proteins in our body that help move glucose, which is a type of sugar, from the blood into our cells where it can be used for energy. They act like doorways or channels, allowing glucose to enter the cells and fuel our bodies. Full definition
They found similar changes in gene expression in the same genes with increased activity of glucose transporters in both the stem cells and the fat cells, Sen noted.
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Since this study was conducted, it appears the reasons for the improvements in glucose tolerance were due to the increased expression of glucose transporter type 4.
The pathway increases the activation of HIF - 1a (hypoxia inducible factor 1 alpha) and produces more glucose transporters on the cell surface — both key changes that promote glycolysis in cancer cells.
The majority of living cells is able to incorporate and metabolize glucose, whereby the transport of this sugar is mediated by facilitative glucose transporters [1].
«Glucose transporters blocked in bacterial meningitis.»
Wray discovered that in human brains there were 2.5 to 3 times as many copies of SLC2A1 as there were in chimpanzee brains, suggesting the presence of more glucose transporters as well.
Cells need carbohydrates; facilitative glucose transporters (GLUTs) bring nutrients in and out of cells.
Similar changes in gene expression in the same genes were found with increased glucose transporter activity in both the fat cells and the stem cells.
Green tea polyphenols inhibit the sodium - dependent glucose transporter of intestinal epithelial cells by a competitive mechanism
Wray guessed that these mutations changed the total number of glucose transporters built in the human brain.
Our muscles contain fewer glucose transporters than in chimps» muscles.
Then he looked at glucose transporters that deliver the sugar to muscles.
In order to make glucose transporters, the cells must first make copies of the SLC2A1 gene to serve as a template.
The researchers then tested the effect of these diets on blood sugar levels and the different glucose transporters in the kidneys.
In their study, researchers used animal models of diabetes and models of diet - induced obesity and insulin resistance to see how insulin resistance and too much sugar or fat affect glucose transporters in the kidney.
One powerful tip not mentioned in the video, is that the best time to do the exercise is just before a meal to open those Glut4 insulin - regulated glucose transporters in your muscle cells, so the carbs from your meal go in to feed your muscles, rather than to be stored as fat.
Glucose transporters also become more numerous in tissues other than muscle, including the liver.
I can't remember being more excited than when I learned about glucose transporters and their ability to move within a cell, called translocation.
Sodium Glucose Transporter 2 Inhibitors (Invokana / Canagliflozin, Farxiga / Dapagliflozin, Jardiance / Empagliflozin)-- These medications interfere with the kidneys pulling glucose from the blood and keeping it in circulation.
Glucose is absorbed in the jejunum with the help of sodium - dependent glucose transporter SGLT1 (S = sodium, GL = glucose, T = transport) only together with sodium (glucose - sodium co-transport).
The ketogenic diet is a first - line treatment for the neurometabolic diseases glucose transporter type 1 (GLUT1) deficiency syndrome and pyruvate dehydrogenase (PDH) deficiency.
Their technique involves attaching a modified form of insulin to glucosamine, a chemical that binds to glucose transporters on red blood cells.
A group of researchers led by Kazuya Kikuchi, professor at the Graduate School of Engineering, Osaka University, clarified the role of a N - glycan chain on glucose transporter type 4 (GLUT4) by developing a method for visualizing intracellular trafficking of proteins.
Derave and co-researchers showed that supplemental creatine increased glucose transporter (glut - 4) expression and muscle glycogen content while improving glucose tolerance in a previously immobilized limb 5.
Protection from disease was conferred by enforced beta cell - specific GnT - 4a protein glycosylation and involved the maintenance of glucose transporter expression and the preservation of glucose transport.
Contrary to popular belief supported by the leading physiology and biochemistry textbooks, there is sufficient population of glucose transporters in all cell membranes at all times to ensure enough glucose uptake to satisfy the cell's respiration, even in the absence of insulin [21].
The research, originally done with just glucose, suggested that consuming more than 60 grams of glucose per hour offered no extra benefits because the body has a limited number of glucose transporters and can carry only 60 grams out of the intestines into the blood and to the muscles.
Specifically, the study — reported online in The Journal of Infectious Diseases — shows that E. coli K1 modulates the protein peroxisome proliferator - activated receptor - gamma (PPAR - γ) and glucose transporter - 1 (GLUT - 1) levels at the blood - brain barrier in human brain microvascular endothelial cells.
Scientists at The Saban Research Institute of Children's Hospital Los Angeles (CHLA) report that glucose transporters, which transfer glucose from the blood to the brain, are inhibited by E. coli K1 during meningitis.
«We found that expression of glucose transporters is completely shut down by bacteria, leaving insufficient fuel for the immune cells to fight off the infection,» said the study's first author, Subramanian Krishnan, PhD, of the Division of Infectious Diseases at CHLA.
The researchers showed that a two - day treatment regimen with partial or selective PPAR - γ agonists (Telmisartan and Rosiglitazone — both FDA - approved drugs) ameliorated the pathological outcomes of infection in mice by inducing expression of glucose transporters.
The USF team believes these novel ketone supplements may be effective in other disorders besides cancer and is conducting ongoing studies to test their potential use in wound healing, epilepsy, amyotrophic lateral sclerosis (ALS), Alzheimer's disease, glucose transporter type 1 (GLUT1) deficiency syndrome, and exercise performance.
Intriguingly, the Duke team discovered that the mutations didn't alter the shape of the glucose transporters.
Triheptanoin is an investigational medicine being developed by Ultragenyx Pharmaceuticals for patients with fatty - acid metabolism disorders and Glucose Transporter Type 1 Deficiency Syndrome, which leads to epileptic seizures in young children.
The glucosamine could then bind to glucose transporters on the surface of a red blood cell, effectively attaching the insulin to the blood cell.
If glucose levels are high, glucose molecules displace the glucosamine in the blood cells» glucose transporters.
The glucosamine then binds to glucose transporters on the surface of a red blood cell, effectively attaching the insulin to the blood cell.
If glucose levels are high, glucose molecules effectively displace the glucosamine in the blood cells» glucose transporters.
They found that certain types of glucose transporters (GLUT and SGLT) as well as their regulatory proteins were present in a higher number in type 2 diabetic rats.
She added, «A new treatment for diabetic patients constitutes blocking the glucose transporter in the kidney to reduce blood glucose levels.
Green fluorescent dyes in this microscopic view mark the presence of the glucose transporter, GLUT1, on the surface of lymphoblastoid cells which go on to form the lymphomas caused by Epstein - Barr virus.