The researchers had discovered higher levels
of glucuronides in the urine of those who were drinking Kombucha so they surmised that there must be glucuronic acid in the KT.
This compound is converted into hydroquinone
glucuronide in the body and excreted from the urine.
It is thought that this excretion of
hydroquinone glucuronide prevents bacteria from adhering to the walls of the urinary tract.
Unlike their distant human relatives, however, tree shrews quickly metabolise most of the alcohol they consume into a by - product called
ethyl glucuronide (EtG).
The enzyme traps
only glucuronide molecules, which are involved in the excretion of toxic compounds in its active site.
Scientific study has identified no less than 13 different flavonoid compounds known as
methylenedioxyflavonol glucuronides found in spinach which function as anticancer agents.
Cats have a genetic deficiency in a metabolic pathway in the liver that breaks down medications, called the «
glucuronide conjugation pathway».
The bioefficacy
of glucuronides and sulfate metabolites, which is what the newer forms of curcumin formulations are claiming are better absorbed, has not been well established.
To test the sensor, they injected a small volume of the sample into the reactor where the enzyme converts
any glucuronide present into the fluorescent product, and a pump then carries this product downstream to a fluorescence detector for analysis (Analytical Chemistry, vol 65, p 3067).
Although many products sold in health - food stores, on the Internet, through MLM companies, and through doctors» networks may claim better absorption, they are measuring curcumin metabolites — especially
the glucuronides — and thus are missing the stronger intended anti-inflammatory effect.
Kombucha tea is sparkling fermented beverage that contains D - saccharic (D - glucaric) acid, which not only binds and pulls toxic metals out of the body, but inhibits glucuronidase, an enzyme that would otherwise hydrolyze
the glucuronides of fat - soluble toxins.