Sentences with phrase «haplotype map»
A haplotype map is a genetic map that shows the variations in DNA sequences called haplotypes, which are groups of genes or markers that tend to be inherited together. This map helps scientists understand how variations in our genes relate to disease susceptibility, response to medications, and other traits in populations. It helps in studying and identifying genetic differences among individuals and populations. Full definition
Related sites Asthma research at the National Institutes of Health Information from the Asthma and Allergy Foundation of America The International Haplotype Mapping Project
sciencemag.org
To study natural selection, the team combed the International Haplotype Map for long stretches of DNA flanked by a single nucleotide polymorphism (SNP, or «snip»)-- that is, an altered base, or «letter,» in the genetic alphabet.
The Hap Map paper, appearing simultaneously online ahead of print in Science, is entitled, «A First - Generation Haplotype Map of Maize;» the corresponding author is Edward S. Buckler.
After months of passing the hat among countries and private companies, the U.S. National Institutes of Health (NIH) announced today that it has garnered the $ 100 million the 3 - year effort to construct a so - called haplotype map is likely to cost.
How many genome - wide association studies in the past two years were made possible by the human haplotype map?
Haplotype mapping of a diploid non-meiotic organism using existing and induced aneuploidies.
At least three major scientific efforts were conceived and initiated during Collins» tenure at NHGRI: the Human Genome Project (HGP), the International Haplotype Map Project (HapMap), and most recently, the 1,000 Genomes Project (TGP).
One of these, the International Haplotype Map, cataloged differences in DNA collected from 270 people of Japanese, Han Chinese, Nigerian, and northern European descent.
Genetic tools still under construction, such as a haplotype map that will be used to discern genetic variation behind common diseases, could further accelerate the search for disease genes.
The investments by Genome Canada should greatly increase Canada's scientific capacity, says Francis Collins, director of the U.S. National Human Genome Research Institute, which has recently announced a $ 32 million competition to work on the haplotype map.
The new money should spur collaborations between scientists from Canada and other countries; the haplotype map project, for example, also involves significant contributions from the United States and the United Kingdom.
Scanning genomes in the haplotype map for these clues, the researchers discovered that 7 percent of human genes fit the profile of a recent adaptation, with most of the change happening from 40,000 years ago to the present.
Ray's lab was in a partnership with Pui Kwok's group at UCSF to serve as one of the genotyping centers for phase I of the International Haplotype Map (HapMap) project, the ambitious effort to map common genetic variation (SNPs) in human populations.
The maize reference genome and the haplotype map are published online today ahead of print in the journal Science, in addition to a supplementary poster on the maize genome placing the plant and the sequencing project in historical and cultural perspective.
The HapMap, a shorthand for haplotype map, gauges diversity in the maize genome by comparing 27 distinct genetic lines of the plant with the reference version.
Moreover, the rapidly growing catalog of single nucleotide polymorphisms in the human population, the decreasing cost of genotyping and whole - genome sequencing, the completion of the reference human DNA sequence and a haplotype map of the entire human genome provide unprecedented opportunities for advancing the study of complex genetic diseases.