Sentences with phrase «high viral load»

Once the drug effect is over, the replication process retains its frequency thereby leading to high viral load in the body.

An estimated 30 to 50 percent of new infections originate from recently infected individuals, who carry higher viral loads.

Specifically, people with higher viral loads progress to AIDS more quickly than those with lower viral loads.

Thus, having a relatively high viral load at the start of treatment could increase the risk for HIV transmission, the scientists suggest.

The first days after HIV infection are very important because sexual partners are exposed to extremely high risks of infection due to the subsequent high viral load in the infected person.

«Transmission via saliva is theoretically possible, but it would require extraordinarily high viral loads that just aren't present in the vast majority of infected people.»

Until recently, researchers believed that receiving HCV - contaminated blood products, where high viral loads directly enter the blood stream, would inevitably lead to infection.

Deadly contaminated sparrows showed high viral loads in all organs (Figure 2), while in the surviving ones, the viral loads were much lower and detected only in some of the organs tested: approximately 104.55 RNA copies per mL for swabs» specimens, 105.09 RNA copies per gram for feathers, and 104.72 RNA copies per gram for organs.

Researchers performed a prospective study of 450 HBV - positive pregnant women with high viral load, or significant HBV in the blood, during the second or third trimester of pregnancy.

Their hypothesis draws on the observation that sooty mangabeys (monkeys) infected with the simian immunodeficiency virus (SIV)-- a pathogen thought to be the ancestor of HIV — have a high viral load but low immune activation.

Recently infected participants are an important target group for intervention because transmission is particularly likely during this time due to high viral loads, lack of immune response, and potentially elevated rates of risky behaviors.

In addition, the investigators found, among the HPTN 052 participants who failed treatment, those who had a higher viral load when they joined the study were more likely to develop resistance to their antiretroviral drugs.

In addition, the investigators found that among the HPTN 052 participants who started antiretroviral therapy early but failed treatment before May 2011, those who had a higher viral load when they joined the study were likely to develop resistance to their antiretroviral drugs.

With any infectious disease, when patients have a high viral load in their bodily fluids, it increases the risk they will pass disease to someone else through direct contact with those fluids.

With HIV, for example, the risk of passing the disease between partners increases with higher viral load: For every 10-fold increase in viral concentration, one 2012 study suggests there is about a threefold increase in the risk of transmission per sexual act.

Patients can remain in this stage for decades with high viral load but no apparent damage to the liver.2 There are two treatment options for HBV immune tolerant patients: pegylated interferon strategy, or nucleos (t) ide analogues.3

It has also been unclear whether a high viral load, or the presence of Zika symptoms, would be associated with risk of harm to the fetus, or if there is a direct relationship between the amount of virus in the blood and severity of symptoms in the mother.

The sooty mangabey, found in West Africa, has somehow adapted to the simian immunodeficiency virus — the nonhuman version of HIV — so that even with a high viral load, it rarely gets sick.

Telbivudine Prevents Vertical Transmission of Hepatitis B Virus From Women With High Viral Loads: A Prospective Long - Term Study, Clinical Gastroenterology and Hepatology, Volume 13 (6): 1170 - 1176.

Studies have also shown that people with higher viral loads are more likely to transmit HIV to others.

Janes, H., Herbeck, J., Tovanabutra, S., Thomas, R., Frahm, N., Duerr, A., Hural, J., Corey, L., self, S., Buchbinder, S., McElrath, J., O'Conell, R., Paris, R., Rerks - Ngarm, S., Nitayaphan, S., Pitisuttihum, P., Kaewkungwal, J., Robb, M., Michael, NL., Mullins, J., Kim, J., Gilbert, P., Rolland, M. HIV - 1 infections with multiple founders are associated with higher viral loads than infections with single founders.

In contrast for ranavirus, a highly virulent pathogen capable of decimating amphibian populations, populations living close to agriculture with high baseline tolerance had higher viral loads than populations far from agriculture with inducible tolerance.

There was no transmission of virus from the sparrows to the chickens, even though the formers did shed virus through cloacal and oral routes and high viral loads were detected on their feathers (Figure 2).

High viral loads were detected in all samples collected post-mortem from birds lethally infected through direct inoculation (Figure 2).