Sentences with phrase «human tumor cell lines»

In studies of laboratory - grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells.

The authors studied a standard panel of 60 established human tumor cell lines representing nine different human cancers, as well as several specimens of human primary ovarian cancer.

Evidence demonstrating its cytostatic activity includes the finding that it inhibits the growth of a broad spectrum of human tumor cell lines in vitro.

Previously, she developed an innovative High Content Screening HTS platform, OncoPanel, to profile therapeutic cancer agents across 240 human tumor cell lines at Ricerca Biosciences (formerly MDS Pharma Services).

In the NCI tumor cell line panel, flavopiridol had significant inhibitory activity against all of the more than 60 human tumor cell lines with no clear selectivity for tumor type.

Flavopiridol inhibits several cellular kinases and has demonstrated cytostatic and cytotoxic activity in vitro and in vivo in numerous human tumor cell lines and xenograft models (including human breast, prostate, and lung carcinoma) at clinically achievable concentrations.

Specifically, they looked for the ability of those compounds to interfere with transcription in human tumor cells obtained through the National Cancer Institute's collection of 60 human tumor cell lines of nine different cancer types, including melanoma and colon cancer.

Peter and colleagues focused their initial studies on a standard panel, known as NCI60, of 60 human tumor cell lines that can genetically be divided into two large groups, which they called superclusters 1 and 2.