Sentences with phrase «hypoxic environment»

To help explain these results, Band and his colleagues looked to the gene expression profiles obtained from their previous studies of blind mole - rats in hypoxic environments.

Professor Ali Tavassoli, who led the study with colleague Dr. Ishna Mistry, explains: «In an effort to better understand the role of HIF - 1 in cancer, and to demonstrate the potential for inhibiting this protein in cancer therapy, we engineered a human cell line with an additional genetic circuit that produces the HIF - 1 inhibiting molecule when placed in a hypoxic environment.

However, in a hypoxic environment, it is activated and initiates a series of events to combat physiological effects of low oxygen.

As the PEC - 01 pancreatic progenitor cells represent a cell type that is present in a developing embryo, they are designed by nature to function in a hypoxic environment, promote vascularization, and differentiate into the critical endocrine cells that populate the pancreatic islets.

When contracting a working muscle during a set, the blood vessels that feed that muscle are compressed, thereby creating a hypoxic environment which stimulates anabolism.