Sentences with phrase «immune cells called macrophages»

In emphysema, a class of immune cells called macrophages flock to the lungs.

But her project — which focuses on how microscopic immune cells called macrophages contribute to muscle injury repair — might not be under way today had it not been for a UNLV initiative introduced to encourage collaborative research projects.

Previous studies have pointed to immune cells called macrophages as the primary immune cell responsible for engulfing and breaking down nerve debris.

Ferumoxytol leaks out of blood vessels in areas of inflammation and is taken up by immune cells called macrophages, which congregate at sites of inflammation.

The drug caused immune cells called macrophages to eject their cholesterol, an important effect because cholesterol - laden macrophages help trigger artery - blocking plaques.

The resulting disease - causing (virulent) parasite forms, called amastigotes, infect and multiply in immune cells called macrophages at the bite site and after dissemination of the infection to secondary sites.

Dr Samantha Ho, the first author of the article, and colleagues in the laboratory of Asst Prof Gasser found that out - of - place DNA in cancer cells activates the immune system by producing a substance called interferon that activates immune cells called macrophages and T cells to kill cancer cells.

In previous research, a team led by the same Artyomov showed that inflammatory immune cells called macrophages produce significant amounts of itaconate when they detect bacteria.

Unlike most bacterial pathogens, which live outside of cells, Listeria hunkers down inside immune cells called macrophages that are sent to destroy it.

An international team of researchers reveals how immune cells called macrophages activate to kill parasitic worms.

Jerrold Olefsky and colleagues at the University of California, San Diego, killed the bone marrow cells in mice that make immune cells called macrophages.

The alpha defensins are then taken up by other immune cells called macrophages.

The Leuven - based VIB researchers have revealed a mechanism that explains why the anti-tumor activity of specific immune cells called macrophages is suppressed during tumor growth.

Because of the bacterium's ability to burrow inside key immune cells called macrophages, some researchers use weakened Listeria with bits of tumor DNA attached to teach the body's immune system to recognize and destroy cancerous cells that might otherwise slip by unnoticed.

Through studies conducted in mice, Oliver M. Steinmetz, MD (University Hospital Hamburg Eppendorf, in Germany) and his colleagues have shown that the messenger protein IL - 6, which is rapidly produced at high levels during an acute inflammatory form of kidney disease, potently dampens activation of tissue - destructive immune cells called macrophages.

Special immune cells called macrophages function like garbage collectors, picking up this waste DNA and breaking it down.

Led by Mauro Ferrari, Ph.D., president and CEO of the Houston Methodist Research Institute, and Joy Wolfram, Ph.D. (now at Mayo Clinic's campus in Jacksonville, Florida), the research showed that chloroquine interfered with immune cells called macrophages, which are used by the body to identify microscopic foreign objects and destroy them.

Elevated levels of MAC are found in the eyes of AMD patients; in addition, anaphylatoxins are known to recruit immune cells called macrophages, and AMD patients also have higher levels of macrophages in their eyes.

In models lacking NLRX1, innate immune cells called macrophages produce higher levels of IL - 6, a signaling molecule that has a central role in colorectal cancer development.

What he found was that this switch, called an ion channel, controls the flow of calcium into immune cells called macrophages.

What's more, it broke up existing plaques by boosting immune cells called macrophages to clear out the plaque.

They've now proposed a series of experiments designed to further explore the role of small snippets of RNA called microRNA in shifting the immune system, and specifically immune cells called macrophages, between these more and less tolerant states.

These proteins promoted tumor growth and metastasis in mice by converting neighboring cancer cells into TICs, stimulating the formation of blood vessels within the tumor and enhancing the recruitment of immune cells called macrophages.

Mice that had fewer cholesterol crystals also had fewer inflammation - causing immune cells called macrophages (red).

In this study, the researchers found that a specific population of immune cells called macrophages have the ability to secrete or produce a protective or healing factor known as Interleukin - 10 (IL - 10), which can interact with receptors on intestinal epithelial cells to promote wound healing.

Moreover, experiments in mice showed that a high - salt diet boosted the activity of immune cells called macrophages, thereby promoting the healing of feet that were infected with a protozoan parasite called Leishmania major.

It's no longer that simple, and the problem is made all the more complicated by the fact that some smooth muscle cells were being misidentified as immune cells called macrophages, while some macrophage - derived cells were masquerading as smooth muscle cells.

There's evidence that immune cells called macrophages in belly fat become inflamed as we get older.

But it's easy to harvest large numbers of their close cousins, immune cells called macrophages.

A team of Massachusetts General Hospital investigators has discovered, for the first time, that the immune cells called macrophages contribute to a type of heart failure for which there currently is no effective treatment.

Under the guidance of a world - renowned cancer biologist, Robert Weinberg, Ph.D., Lu is focusing on how metastatic breast cancer cells interact with a subset of immune cells called macrophages, which normally are capable of engulfing — literally eating — infected, damaged, or cancerous cells.