Sentences with phrase «immune destruction»

The sugar made it hard for antibodies to stick, so it helped the virus avoid immune destruction.

In fact, some researchers are even suggesting that lung cancers use the PD - 1 pathway to escape immune destruction in the first place.

The selective pressure of the competent immune system «edits» the tumor by selecting for cells that can avoid immune destruction.

At least 50 % of diabetic dogs have type 1 diabetes based on present evidence of immune destruction of β - cells.

This is the first study to show the role that type I interferon plays in driving the body's immune destruction during HIV infection, said Scott Kitchen, associate professor of medicine in the division of hematology / oncology at the David Geffen School of Medicine at UCLA and senior author of the study published in the peer - reviewed Journal of Clinical Investigation.

Interestingly, when parental d42m1 sarcoma cells were transplanted into wild - type mice, around 20 % of recipients developed «escape» tumors which evaded immune destruction and progressed (escape clones).

Despite these observations, the mechanisms employed by a growing tumour to avoid immune destruction remain unclear, thus increasing our understanding of anti-tumour immunity and the suppressive networks at play during malignant transition will be fundamental to the development of improved strategies and design of new, targeted therapeutic platforms.

When implanted, PEC - 01 cells are expected to differentiate into pancreatic islet cells that produce insulin and other hormones that regulate blood sugar, while the Encaptra device is designed to protect the cells from immune destruction.

Researchers have found that some mothers of autistic children create antibodies to the brain tissue of their fetus, meaning the child is a born with a brain already developmentally imbalanced by immune destruction.

A small percentage of Addisonians go on to develop immune destruction of other organs.

While dogs tend to develop diabetes mellitus secondary to either immune destruction of the pancreatic beta cells or severe pancreatitis, cats tend to develop diabetes mellitus secondary to pancreatitis or amyloidosis.

Cancer cells can hijack this checkpoint by binding to the PD - 1 receptor on T cells with a ligand called PD - L1, thereby escaping immune destruction.

Two new emerging principles (reprogramming cellular energetics and avoiding immune destruction) became evident, as did a second enabling characteristic (inflammation).

Further, they present two new hallmarks — reprogramming of energy metabolism and evasion of immune destruction — that have emerged as critical capabilities of cancer cells.

Additional work demonstrated that using antibodies to block this interaction disarmed the tumors, rendering them vulnerable to immune destruction.

The most common cause (at least 95 % of cases) is immune destruction of the thyroid gland.

The pathogenic mechanisms responsible for decreased insulin production and secretion are multiple, but usually they are related to destruction of islet cells, secondary to either immune destruction or severe pancreatitis (dogs) or amyloidosis (cats).

By modifying its Osp's, the spirochete is able to change its presentation to the mammalian host's immune system thus escaping immune destruction.